Girotti F, Soliveri P, Carella F, Piccolo I, Caffarra P, Musicco M, Caraceni T
Istituto Neurologico C. Besta, Milan, Italy.
J Neurol Neurosurg Psychiatry. 1988 Dec;51(12):1498-502. doi: 10.1136/jnnp.51.12.1498.
The frequency of dementia, the clinical characteristics and the pattern of cognitive impairment were studied in 147 unselected Parkinsonian patients. Twenty-one patients (14.28%) were judged to be demented. They had a more severe and widespread cognitive deficit although they were affected particularly in those tests that already discriminated Parkinsonian patients from controls. A direct comparison of Parkinsonian dementia with other types of dementia is needed to validate the concept of subcortical dementia.
对147例未经挑选的帕金森病患者的痴呆发生率、临床特征及认知障碍模式进行了研究。21例患者(14.28%)被判定为痴呆。尽管他们在那些已将帕金森病患者与对照组区分开来的测试中受到特别影响,但他们存在更严重、更广泛的认知缺陷。需要将帕金森病痴呆与其他类型的痴呆进行直接比较,以验证皮质下痴呆的概念。