Australian and New Zealand Intensive Care Research Centre (ANZIC-RC), School of Public Health and Preventive Medicine, Monash University, Melbourne, Australia.
Alfred Health, Melbourne, Australia.
Qual Life Res. 2024 Jan;33(1):17-29. doi: 10.1007/s11136-023-03487-x. Epub 2023 Aug 2.
Health-related quality of life (HRQoL) is a patient-reported measure of health status. However, research on the psychometric properties of HRQoL instruments used post-critical care is less common. We conducted a systematic review assessing the psychometric properties of HRQoL instruments used in adult survivors following critical illness.
Three databases were systematically searched between 1990 and June 2022. Screening articles for eligibility, we selected either development studies for new tools or studies that evaluated psychometric properties, and whose target population represented adult survivors following critical illness. Methodological quality was assessed using the COnsensus-Based Standards for the selection of health Measurement INstruments (COSMIN) checklist. The results of each psychometric property were then assessed for criteria of good psychometric properties (sufficient, insufficient or indeterminate) and qualitatively summarised. Finally, we graded the quality of the evidence using a modified GRADE approach.
We retrieved 13 eligible studies from 2,983 records identifying 10 HRQoL instruments used post-critical illness. While high-quality evidence for the considered PROMs was limited primarily due to risk of bias, seven instruments demonstrated sufficient levels of reliability, four instruments presented sufficient hypothesis testing, and two instruments showed sufficient responsiveness. Except the Short Form-36, evidence for psychometric properties of other individual measures was limited to a few studies.
There was limited evidence demonstrated for the psychometric properties of the included PROMs evaluating HRQoL. Further research is warranted to evaluate the psychometric properties of HRQoL measures, strengthening the evidence for administering these instruments in survivors following critical illness.
健康相关生活质量（HRQoL）是一种患者报告的健康状况衡量标准。然而，针对重症监护后使用的 HRQoL 工具的心理测量学特性的研究则相对较少。我们进行了一项系统综述，评估了用于重症后成年幸存者的 HRQoL 工具的心理测量学特性。
我们于 1990 年至 2022 年 6 月期间系统地检索了三个数据库。通过筛选文章以确定其是否符合纳入标准，我们选择了新工具的开发研究或评估心理测量学特性的研究，且其目标人群为重症后成年幸存者。使用共识基础的健康测量工具选择标准（COSMIN）清单评估方法学质量。然后，我们根据良好心理测量学特性的标准（充分、不充分或不确定）评估每个心理测量特性的结果，并进行定性总结。最后，我们使用改良的 GRADE 方法对证据质量进行分级。
我们从 2983 条记录中检索到 13 项符合纳入标准的研究，确定了 10 种用于重症后患者的 HRQoL 工具。由于存在偏倚风险，主要考虑的 PROM 工具的高质量证据有限，但有 7 种工具的可靠性达到了充分水平，4 种工具的假设检验达到了充分水平，2 种工具的反应度达到了充分水平。除了简短表单-36 外，其他个别测量工具的心理测量特性证据仅限于少数研究。
纳入的用于评估 HRQoL 的 PROM 工具的心理测量学特性的证据有限。需要进一步研究来评估 HRQoL 测量工具的心理测量学特性，以加强在重症后幸存者中使用这些工具的证据。
