Ali Adil, Ali Muhammad, Nisar Zonaira, Shah Syed Muhammad Ali, Mustafa Imtiaz, Nisar Jaweria, Asif Rizwan
School of Science, University of Management and Technology, Lahore, Pakistan.
Department of Eastern Medicine, Government College University Faisalabad, Faisalabad, Pakistan.
Bioinform Biol Insights. 2023 Jul 31;17:11779322231189374. doi: 10.1177/11779322231189374. eCollection 2023.
The emergence of medication resistance and unfavorable side effects from existing antibiotics has prompted the quest for novel antimicrobial agents over the last 2 decades. Plant extracts have been shown to have antibacterial effects in numerous studies. The objective of this study was the evaluation of the antibacterial effect of economically important medicinal plants found in Pakistan. (flowers and leaves), (flowers and leaves), (whole plant), (whole plant), and (whole plant) were used against , and Water and ethanol extracts were obtained from different parts of the plants. To evaluate the antibacterial effect of these plants, qualitative assay agar well diffusion method was performed. The minimum inhibitory concentration (MIC) was determined by the broth micro dilution method. Results revealed that the highest inhibition zone (18 mm) was shown by ethanol extract of flower against . Ethanol extract of plants is best for all 3 tested microbes (, and ). The results concluded that all these plants have abilities to fight against these tested bacteria. Ethanol extract of flower has the highest activity against .
在过去20年里,现有抗生素耐药性的出现以及不良副作用促使人们寻找新型抗菌剂。众多研究表明植物提取物具有抗菌作用。本研究的目的是评估在巴基斯坦发现的具有经济重要性的药用植物的抗菌效果。(花和叶)、(花和叶)、(全株)、(全株)以及(全株)被用于对抗、和。从植物的不同部位获得水提取物和乙醇提取物。为评估这些植物的抗菌效果,采用了定性测定琼脂扩散法。通过肉汤微量稀释法测定最低抑菌浓度(MIC)。结果显示,花的乙醇提取物对显示出最高抑菌圈(18毫米)。植物的乙醇提取物对所有3种受试微生物(、和)效果最佳。结果表明,所有这些植物都有对抗这些受试细菌的能力。花的乙醇提取物对的活性最高。