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从草药材料中筛选和分离抗生素抗性抑制剂——韩国芳香草药挥发性成分的抗性抑制作用

Screening and isolation of antibiotic resistance inhibitors from herb materials-resistance inhibition of volatile components of Korean aromatic herbs.

作者信息

Lee C K, Kim H, Moon K H, Shin K H

机构信息

College of Pharmacy, Kyungsung University, Pusan, Korea.

出版信息

Arch Pharm Res. 1998 Feb;21(1):62-6. doi: 10.1007/BF03216754.

DOI:10.1007/BF03216754
PMID:9875516
Abstract

The resistance inhibitory activities of 54 odorant mixtures (essential oil) from 41 Korean aromatic herbs were tested against multi-drug resistant Staphylococcus aureus SA2, which has resistances to 10 usual antibiotics including chloramphenicol. As results, combinations of 28 kinds of samples from 21 herbs and chloramphenicol have resistance inhibitory activities in dose dependent manner.

摘要

对来自41种韩国芳香草药的54种气味混合物（精油）针对多重耐药性金黄色葡萄球菌SA2进行了耐药抑制活性测试，该菌株对包括氯霉素在内的10种常用抗生素具有耐药性。结果显示，来自21种草药的28种样品与氯霉素的组合具有剂量依赖性的耐药抑制活性。

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