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一种用于癌症患者早期血栓形成预测的微流控方法。

A microfluidic approach for early prediction of thrombosis in patients with cancer.

机构信息

School of Biomedical Engineering, Faculty of Engineering, The University of Sydney, Darlington, NSW 2008, Australia.

Charles Perkins Centre, The University of Sydney, Camperdown, NSW 2006, Australia.

出版信息

Cell Rep Methods. 2023 Jul 13;3(7):100536. doi: 10.1016/j.crmeth.2023.100536. eCollection 2023 Jul 24.

DOI:10.1016/j.crmeth.2023.100536
PMID:37533648
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10391554/
Abstract

Li and colleagues have made a notable advancement in predicting cancer-associated thrombosis with a microfluidic device that monitors circulating platelet activity. This tool could improve the management of thrombotic events in patients with cancer, guiding timely treatment and potentially reducing mortality.

摘要

李和他的同事们在使用微流控设备监测循环血小板活性来预测癌症相关血栓方面取得了显著进展。该工具可以改善癌症患者血栓事件的管理,指导及时治疗并可能降低死亡率。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c097/10391554/bb0ada0b6957/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c097/10391554/bb0ada0b6957/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c097/10391554/bb0ada0b6957/gr1.jpg

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1
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Cell Rep Methods. 2023 Jul 13;3(7):100536. doi: 10.1016/j.crmeth.2023.100536. eCollection 2023 Jul 24.
2
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本文引用的文献

1
Monitoring circulating platelet activity to predict cancer-associated thrombosis.监测循环血小板活性以预测癌症相关血栓形成。
Cell Rep Methods. 2023 Jun 27;3(7):100513. doi: 10.1016/j.crmeth.2023.100513. eCollection 2023 Jul 24.
2
3D spheroid-microvasculature-on-a-chip for tumor-endothelium mechanobiology interplay.用于肿瘤-内皮细胞力学生物学相互作用的芯片上3D球体-微血管系统
Biomed Mater. 2023 Jul 27;18(5). doi: 10.1088/1748-605X/ace7a4.
3
Point-of-Care Blood Coagulation Assay Based on Dynamic Monitoring of Blood Viscosity Using Droplet Microfluidics.
基于液滴微流控技术动态监测血液黏度的即时凝血检测。
ACS Sens. 2022 Aug 26;7(8):2170-2177. doi: 10.1021/acssensors.1c02360. Epub 2022 May 10.
4
Cancer-associated venous thromboembolism.癌症相关静脉血栓栓塞症。
Nat Rev Dis Primers. 2022 Feb 17;8(1):11. doi: 10.1038/s41572-022-00336-y.
5
Platelet Mechanobiology Inspired Microdevices: From Hematological Function Tests to Disease and Drug Screening.血小板力学生物学启发的微型器件:从血液学功能测试到疾病与药物筛选
Front Pharmacol. 2022 Jan 20;12:779753. doi: 10.3389/fphar.2021.779753. eCollection 2021.