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针对年轻人身体活动不足和/或营养问题的数字干预措施:欧洲癌症预防组织系统评价综述

Digital interventions to moderate physical inactivity and/or nutrition in young people: a Cancer Prevention Europe overview of systematic reviews.

作者信息

McDermott Kevin T, Noake Caro, Wolff Robert, Bauld Linda, Espina Carolina, Foucaud Jérôme, Steindorf Karen, Thorat Mangesh A, Weijenberg Matty P, Schüz Joachim, Kleijnen Jos

机构信息

Kleijnen Systematic Reviews Ltd., York, United Kingdom.

Usher Institute and SPECTRUM Consortium, University of Edinburgh, Edinburgh, United Kingdom.

出版信息

Front Digit Health. 2023 Jul 4;5:1185586. doi: 10.3389/fdgth.2023.1185586. eCollection 2023.

Abstract

BACKGROUND

Strategies to increase physical activity (PA) and improve nutrition would contribute to substantial health benefits in the population, including reducing the risk of several types of cancers. The increasing accessibility of digital technologies mean that these tools could potentially facilitate the improvement of health behaviours among young people.

OBJECTIVE

We conducted a review of systematic reviews to assess the available evidence on digital interventions aimed at increasing physical activity and good nutrition in sub-populations of young people (school-aged children, college/university students, young adults only (over 18 years) and both adolescent and young adults (<25 years)).

METHODS

Searches for systematic reviews were conducted across relevant databases including KSR Evidence (www.ksrevidence.com), Cochrane Database of Systematic Reviews (CDSR) and Database of Abstracts of Reviews of Effects (DARE; CRD). Records were independently screened by title and abstract by two reviewers and those deemed eligible were obtained for full text screening. Risk of bias (RoB) was assessed with the Risk of Bias Assessment Tool for Systematic Reviews (ROBIS) tool. We employed a narrative analysis and developed evidence gap maps.

RESULTS

Twenty-four reviews were included with at least one for each sub-population and employing a range of digital interventions. The quality of evidence was limited with only one of the 24 of reviews overall judged as low RoB. Definitions of "digital intervention" greatly varied across systematic reviews with some reported interventions fitting into more than one category (i.e., an internet intervention could also be a mobile phone or computer intervention), however definitions as reported in the relevant reviews were used. No reviews reported cancer incidence or related outcomes. Available evidence was limited both by sub-population and type of intervention, but evidence was most pronounced in school-aged children. In school-aged children eHealth interventions, defined as school-based programmes delivered by the internet, computers, tablets, mobile technology, or tele-health methods, improved outcomes. Accelerometer-measured (Standardised Mean Difference [SMD] 0.33, 95% Confidence Interval [CI]: 0.05 to 0.61) and self-reported (SMD: 0.14, 95% CI: 0.05 to 0.23) PA increased, as did fruit and vegetable intake (SMD: 0.11, 95% CI: 0.03 to 0.19) (review rated as low RoB, minimal to considerable heterogeneity across results). No difference was reported for consumption of fat post-intervention (SMD: -0.06, 95% CI: -0.15 to 0.03) or sugar sweetened beverages(SSB) and snack consumption combined post-intervention (SMD: -0.02, 95% CI:-0.10 to 0.06),or at the follow up (studies reported 2 weeks to 36 months follow-up) after the intervention (SMD:-0.06, 95% CI: -0.15 to 0.03) (review rated low ROB, minimal to substantial heterogeneity across results). Smartphone based interventions utilising Short Messaging Service (SMS), app or combined approaches also improved PA measured using objective and subjective methods (SMD: 0.44, 95% CI: 0.11 to 0.77) when compared to controls, with increases in total PA [weighted mean difference (WMD) 32.35 min per day, 95% CI: 10.36 to 54.33] and in daily steps (WMD: 1,185, 95% CI: 303 to 2,068) (review rated as high RoB, moderate to substantial heterogeneity across results). For all results, interpretation has limitations in terms of RoB and presence of unexplained heterogeneity.

CONCLUSIONS

This review of reviews has identified limited evidence that suggests some potential for digital interventions to increase PA and, to lesser extent, improve nutrition in school-aged children. However, effects can be small and based on less robust evidence. The body of evidence is characterised by a considerable level of heterogeneity, unclear/overlapping populations and intervention definitions, and a low methodological quality of systematic reviews. The heterogeneity across studies is further complicated when the age (older vs. more recent), interactivity (feedback/survey vs. no/less feedback/surveys), and accessibility (type of device) of the digital intervention is considered. This underscores the difficulty in synthesising evidence in a field with rapidly evolving technology and the resulting challenges in recommending the use of digital technology in public health. There is an urgent need for further research using contemporary technology and appropriate methods.

摘要

背景

增加身体活动(PA)和改善营养的策略将为人群带来显著的健康益处,包括降低几种癌症的风险。数字技术的日益普及意味着这些工具可能有助于改善年轻人的健康行为。

目的

我们对系统评价进行了综述,以评估关于旨在增加年轻人亚群体(学龄儿童、大学生、仅年轻人(18岁以上)以及青少年和年轻人(<25岁))的身体活动和良好营养的数字干预措施的现有证据。

方法

在包括KSR Evidence(www.ksrevidence.com)、Cochrane系统评价数据库(CDSR)和效果评价文摘数据库(DARE;CRD)在内的相关数据库中搜索系统评价。由两名评审员独立根据标题和摘要筛选记录,并获取被认为符合条件的记录进行全文筛选。使用系统评价的偏倚风险评估工具(ROBIS)评估偏倚风险(RoB)。我们采用叙述性分析并绘制了证据差距图。

结果

纳入了24项综述,每个亚群体至少有一项,采用了一系列数字干预措施。证据质量有限,24项综述中只有一项总体被判定为低RoB。“数字干预”的定义在系统评价中差异很大,一些报告的干预措施属于多个类别(例如,互联网干预也可能是手机或计算机干预),但使用的是相关综述中报告的定义。没有综述报告癌症发病率或相关结果。现有证据在亚群体和干预类型方面都有限,但在学龄儿童中证据最为明显。在学龄儿童中,电子健康干预(定义为由互联网、计算机、平板电脑、移动技术或远程医疗方法提供的基于学校的项目)改善了相关结果。通过加速度计测量的PA(标准化均值差[SMD]0.33,95%置信区间[CI]:0.05至0.61)和自我报告的PA(SMD:0.14,95%CI:0.05至0.23)增加,水果和蔬菜摄入量也增加(SMD:0.11,95%CI:0.03至0.19)(该综述被评为低RoB,结果间异质性最小到中等)。干预后脂肪摄入量(SMD:-0.06,95%CI:-0.15至0.03)、糖饮料(SSB)和零食摄入量总和(SMD:-0.02,95%CI:-0.10至0.06)或干预后随访(研究报告随访时间为2周至36个月)时均未发现差异(SMD:-0.06,95%CI:-0.15至0.03)(该综述被评为低ROB,结果间异质性最小到较大)。与对照组相比,基于智能手机利用短消息服务(SMS)、应用程序或组合方法的干预措施也改善了通过客观和主观方法测量的PA(SMD:0.44,95%CI:0.11至0.77),总PA增加[加权均值差(WMD)每天32.35分钟,95%CI:10.36至54.33],每日步数增加(WMD:1185,95%CI:303至2068)(该综述被评为高RoB,结果间异质性中等至较大)。对于所有结果,在RoB和存在无法解释的异质性方面,解释都存在局限性。

结论

本综述的综述发现有限的证据表明数字干预在增加学龄儿童的PA以及在较小程度上改善营养方面有一些潜力。然而,效果可能很小且基于不太可靠的证据。证据主体的特点是存在相当程度的异质性、不明确/重叠的人群和干预定义,以及系统评价的方法学质量较低。当考虑数字干预的年龄(较旧与较新)、交互性(反馈/调查与无/较少反馈/调查)和可及性(设备类型)时,各研究之间的异质性进一步复杂化。这凸显了在技术快速发展的领域综合证据的困难以及在公共卫生中推荐使用数字技术所面临的挑战。迫切需要使用当代技术和适当方法进行进一步研究。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6947/10393256/d7aa0dbfaa1a/fdgth-05-1185586-g001.jpg

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