Cappellari Alberto M, Mariani Stefano, Bruschi Gaia
Department of Neuroscience and Mental Health, Fondazione IRCCS Cà Granda Ospedale Maggiore Policlinico, Milan, Italy.
Department of Medical-Surgical and Transplant Pathophysiology, University of Milan, Milan, Italy.
Front Pediatr. 2023 Jul 18;11:1151770. doi: 10.3389/fped.2023.1151770. eCollection 2023.
Febrile seizures (FS) and benign convulsions in children with mild gastroenteritis (CwG) are acute symptomatic seizures, transiently occurring in infants and young children, probably related to the immaturity of the brain. Our paper aims to review the literature data on patients with FS and CwG.
A review of series of patients with FS and CwG was performed by literature search on PubMed January 1960 to October 2022. Several parameters were considered, including epidemiology, pathophysiology, clinical features, electroencephalographic findings and other diagnostic studies, and treatment.
FS and CwG share an age-dependent course, but they show significant differences in the pathophysiology, clinical features, diagnostic studies, and treatment.
Acute symptomatic seizures include seizures that are caused by acute structural brain pathologies, such as stroke, as well as seizures that are provoked by a reversible factor, such as hyponatraemia, although the two groups should be not equated. Furthermore, FS and CwG should be set apart as "age-dependent acute symptomatic seizures", reinforcing the concept of their self-limited course over a certain period.
热性惊厥（FS）和轻度胃肠炎患儿的良性惊厥（CwG）是急性症状性惊厥，在婴幼儿中短暂发生，可能与大脑发育不成熟有关。我们的论文旨在综述关于FS和CwG患者的文献数据。
通过在PubMed上检索1960年1月至2022年10月的文献，对FS和CwG患者系列进行综述。考虑了几个参数，包括流行病学、病理生理学、临床特征、脑电图结果及其他诊断研究和治疗。
FS和CwG有年龄依赖性病程，但它们在病理生理学、临床特征、诊断研究和治疗方面存在显著差异。
急性症状性惊厥包括由急性结构性脑病变（如中风）引起的惊厥，以及由可逆因素（如低钠血症）诱发的惊厥，尽管这两组不应等同。此外，FS和CwG应作为“年龄依赖性急性症状性惊厥”区分开来，强化它们在一定时期内自限性病程的概念。
