Department of Endodontics, Hospital of Stomatology, Jilin University, Changchun, China.
Drug Dev Res. 2023 Nov;84(7):1376-1394. doi: 10.1002/ddr.22096. Epub 2023 Aug 3.
Catalpol is a kind of iridoid glucoside, widely found in a variety of plants, mostly extracted from the rhizome of the traditional medicinal herb rehmanniae. It has various biological activities such as anti-inflammatory, antioxidant, and antitumor. The anti-inflammatory effects of catalpol have been demonstrated in a variety of diseases, such as neurological diseases, atherosclerosis, renal diseases, respiratory diseases, digestive diseases, bone and joint diseases, eye diseases, and periodontitis. The purpose of this review is to summarize the existing literature on the anti-inflammatory effects of catalpol in a variety of inflammatory diseases over the last decade and to focus on the anti-inflammatory mechanisms of catalpol.
梓醇是一种环烯醚萜类糖苷，广泛存在于多种植物中，主要从传统中药地黄的根茎中提取。它具有多种生物活性，如抗炎、抗氧化和抗肿瘤。梓醇的抗炎作用已在多种疾病中得到证实，如神经疾病、动脉粥样硬化、肾脏疾病、呼吸系统疾病、消化系统疾病、骨关节炎、眼病和牙周炎。本综述的目的是总结过去十年中梓醇在多种炎症性疾病中的抗炎作用的现有文献，并重点介绍梓醇的抗炎机制。
