Ye Mao, Xu Tao, Liu Min, Zhu Yatong, Yuan Dundong, Zhang Hao, Qin Ming, Sun Litao
SEU-FEI Nano-Pico Center, Key Laboratory of MEMS of Ministry of Education, School of Electronic Science and Engineering, Southeast University, Nanjing 210096, China.
Nano Lett. 2023 Aug 23;23(16):7319-7326. doi: 10.1021/acs.nanolett.3c01532. Epub 2023 Aug 3.
Reactive oxygen species (ROS) widely participate in a variety of chemical reactions in biological and chemical applications. However, due to the extremely short lifetime of most ROS, conventional ROS-detecting techniques cannot show real-time dynamic changes of ROS-driven chemical reactions and identify the actual role of individual reactive species in these reactions. Herein, using liquid cell TEM complemented by experiments, we directly visualize ROS-driven rapid etching of Prussian bule (PB) in real time and identify the dominant reactive species in etching processes. The results reveal that highly oxidative OH is the dominant reactive radical in ROS-driven rapid chemical etching and hollow mesoporous PB nanoparticles can be synthesized on a minute-level time scale via OH-dominated rapid etching. This work provides insight into ROS-related oxidation, which can continuously improve our understanding of ROS chemistry and make ROS more widely applicable in advanced chemical etching.
活性氧（ROS）广泛参与生物和化学应用中的各种化学反应。然而，由于大多数ROS的寿命极短，传统的ROS检测技术无法显示ROS驱动的化学反应的实时动态变化，也无法确定单个活性物种在这些反应中的实际作用。在此，我们使用液体细胞透射电子显微镜（TEM）并辅以实验，实时直接观察ROS驱动的普鲁士蓝（PB）快速蚀刻过程，并确定蚀刻过程中的主要活性物种。结果表明，高氧化性的OH是ROS驱动的快速化学蚀刻中的主要活性自由基，通过以OH为主导的快速蚀刻，可以在分钟级的时间尺度上合成中空介孔PB纳米颗粒。这项工作为ROS相关的氧化反应提供了深入了解，有助于不断增进我们对ROS化学的理解，并使ROS在先进化学蚀刻中得到更广泛的应用。
