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放疗联合免疫治疗宫颈癌:现状与未来

Combining Radiotherapy with Immunotherapy in Cervical Cancer: Where Do We Stand and Where Are We Going?

机构信息

Department of Obstetrics, Shenzhen Longhua District Central Hospital, Shenzhen, 518110, China.

Department of General Medicine, Shenzhen Longhua District Central Hospital, Shenzhen, 518110, China.

出版信息

Curr Treat Options Oncol. 2023 Oct;24(10):1378-1391. doi: 10.1007/s11864-023-01128-6. Epub 2023 Aug 3.

Abstract

Combining immunotherapy and radiotherapy as a treatment strategy for cervical cancer has attracted increasing attention. The primary objective of this review is to provide an up-to-date summary of the knowledge regarding the combined use of radiotherapy and immunotherapy for treating cervical cancer. This review discusses the biological rationale combining immunotherapy with radiotherapy in a clinical setting and presents supporting evidence for the combination strategy based on both safety and effectiveness data. Additionally, we discuss the potential and challenges of combining radiotherapy and immunotherapy in clinical practice.

摘要

将免疫疗法与放射疗法相结合作为宫颈癌的治疗策略已引起广泛关注。本文旨在对放疗联合免疫治疗宫颈癌的相关知识进行综述。本文讨论了在临床环境中联合使用免疫疗法和放射疗法的生物学原理,并根据安全性和有效性数据为联合治疗策略提供了支持证据。此外,本文还讨论了在临床实践中联合应用放疗和免疫疗法的潜力和挑战。

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