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2017 年至 2022 年加拿大膝关节和髋关节骨关节炎 GLA:D® 项目:项目参与者的综合情况简介。

The GLA:D® Canada program for knee and hip osteoarthritis: A comprehensive profile of program participants from 2017 to 2022.

机构信息

Schroeder Arthritis Institute, Krembil Research Institute, University Health Network, Toronto, Ontario, Canada.

Center for Muscle and Joint Health, Department of Sports Science and Clinical Biomechanics, University of Southern Denmark, Odense, Denmark.

出版信息

PLoS One. 2023 Aug 3;18(8):e0289645. doi: 10.1371/journal.pone.0289645. eCollection 2023.

Abstract

BACKGROUND

The Good Life with osteoArthritis in Denmark (GLA:D®) program was implemented in Canada in 2017 with the aim of making treatment guideline-recommended care available to the 4 million Canadians with knee and hip osteoarthritis (OA). This report describes the GLA:D® Canada program, registry and data collection procedures, and summarizes the sociodemographic and clinical profile of participants with knee and hip OA to inform the scientific research community of the availability of these data for future investigations and collaborations.

METHODS

The GLA:D® program consists of three standardized components: a training course for health care providers, a group-based patient education and exercise therapy program, and a participant data registry. Patients seeking care for knee or hip OA symptoms and enrolling in GLA:D® are given the option to provide data to the GLA:D® Canada registry. Participants agreeing to provide data complete a pre-program survey and are followed up after 3-, and 12-months. Data collected on the pre-program and follow-up surveys include sociodemographic factors, clinical characteristics, health status measures, and objective physical function tests. These variables were selected to capture information across relevant health constructs and for future research investigations.

RESULTS

At 2022 year-end, a total of 15,193 (11,228 knee; 3,965 hip) participants were included in the GLA:D® Canada registry with 7,527 (knee; 67.0%) and 2,798 (hip; 70.6%) providing pre-program data. Participants were 66 years of age on average, predominately female, and overweight or obese. Typically, participants had knee or hip problems for multiple years prior to initiating GLA:D®, multiple symptomatic knee and hip joints, and at least one medical comorbidity. Before starting the program, the average pain intensity was 5 out of 10, with approximately 2 out of 3 participants using pain medication and 1 in 3 participants reporting a desire to have joint surgery. Likewise, 9 out 10 participants report having previously been given a diagnosis of OA, with 9 out 10 also reporting having had a radiograph, of which approximately 87% reported the radiograph showed signs of OA.

CONCLUSION

We have described the GLA:D® Canada program, registry and data collection procedures, and provided a detailed summary to date of the profiles of participants with knee and hip OA. These individual participant data have the potential to be linked with local health administrative data registries and comparatively assessed with other international GLA:D® registries. Researchers are invited to make use of these rich datasets and participate in collaborative endeavours to tackle questions of Canadian and global importance for a large and growing clinical population of individuals with hip and knee OA.

摘要

背景

丹麦的“关节炎美好生活”(GLA:D®)项目于 2017 年在加拿大实施,旨在为 400 万患有膝和髋骨关节炎(OA)的加拿大人提供治疗指南推荐的护理。本报告介绍了 GLA:D®加拿大项目、登记处和数据收集程序,并总结了膝和髋 OA 患者的社会人口统计学和临床特征,为科学界提供了这些数据,以便未来进行研究和合作。

方法

GLA:D® 项目由三个标准化组成部分组成:医疗保健提供者培训课程、基于小组的患者教育和运动疗法计划以及参与者数据登记处。寻求膝或髋 OA 症状治疗并参加 GLA:D®的患者可选择向 GLA:D®加拿大登记处提供数据。同意提供数据的参与者完成项目前调查,并在 3 个月和 12 个月后进行随访。在项目前和随访调查中收集的数据包括社会人口统计学因素、临床特征、健康状况衡量标准和客观身体功能测试。这些变量是为了在相关健康结构中捕获信息并为未来的研究调查而选择的。

结果

截至 2022 年年末,GLA:D®加拿大登记处共纳入 15193 名(11228 名膝;3965 名髋)参与者,其中 7527 名(膝;67.0%)和 2798 名(髋;70.6%)提供了项目前数据。参与者的平均年龄为 66 岁,主要为女性,超重或肥胖。通常,参与者在开始 GLA:D®之前已经有多年的膝或髋问题,多个有症状的膝和髋关节,以及至少一种合并症。在开始该项目之前,平均疼痛强度为 10 分中的 5 分,约有 2/3 的参与者使用止痛药,1/3 的参与者表示希望进行关节手术。同样,9/10 的参与者报告之前被诊断为 OA,其中 9/10 的参与者也报告进行过 X 光检查,其中约 87%的报告显示 X 光检查显示出 OA 的迹象。

结论

我们描述了 GLA:D®加拿大项目、登记处和数据收集程序,并提供了迄今为止膝和髋 OA 患者特征的详细摘要。这些个体参与者数据有可能与当地健康管理数据登记处进行链接,并与其他国际 GLA:D®登记处进行比较评估。我们邀请研究人员利用这些丰富的数据集并参与合作努力,以解决加拿大和全球范围内对大量不断增长的髋和膝 OA 患者群体具有重要意义的问题。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/69a5/10399832/230db1b83fc7/pone.0289645.g001.jpg

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