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非洲裔美国人的卡托卡特炉遗传遗产。

The genetic legacy of African Americans from Catoctin Furnace.

机构信息

23andMe, Inc., Sunnyvale, CA 94043, USA.

Department of Human Evolutionary Biology, Harvard University, Cambridge, MA 02138, USA.

出版信息

Science. 2023 Aug 4;381(6657):eade4995. doi: 10.1126/science.ade4995.

Abstract

Few African Americans have been able to trace family lineages back to ancestors who died before the 1870 United States Census, the first in which all Black people were listed by name. We analyzed 27 individuals from Maryland's Catoctin Furnace African American Cemetery (1774-1850), identifying 41,799 genetic relatives among consenting research participants in 23andMe, Inc.'s genetic database. One of the highest concentrations of close relatives is in Maryland, suggesting that descendants of the Catoctin individuals remain in the area. We find that many of the Catoctin individuals derived African ancestry from the Wolof or Kongo groups and European ancestry from Great Britain and Ireland. This study demonstrates the power of joint analysis of historical DNA and large datasets generated through direct-to-consumer ancestry testing.

摘要

很少有非裔美国人能够追溯到 1870 年美国人口普查(第一次列出所有黑人的名字)之前去世的祖先的家族谱系。我们分析了马里兰州卡托卡特因炉非裔美国人公墓(1774-1850 年)的 27 个人,在 23andMe, Inc. 的基因数据库中确定了同意参与研究的 41799 名遗传亲属。近亲最集中的地区之一是马里兰州,这表明卡托卡特因个体的后代仍在该地区。我们发现,卡托卡特因个体的许多非洲血统来自沃洛夫人或刚果人,欧洲血统来自英国和爱尔兰。这项研究展示了联合分析历史 DNA 和通过直接面向消费者的基因检测生成的大型数据集的力量。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d9ae/10958645/228f79dba6a7/nihms-1962424-f0007.jpg

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