University of Health Sciences, Derince Training and Research Hospital, Department of Neurology, Kocaeli, Turkey.
Duzce University, Faculty of Medicine, Department of Neurology, Duzce, Turkey.
Arq Neuropsiquiatr. 2023 Aug;81(8):734-739. doi: 10.1055/s-0043-1771494. Epub 2023 Aug 3.
Peripheral nerve block (PNB) is usually performed in patients with migraine who are resistant to treatment with medications.
To compare the efficacy of PNB alone and PNB combined with prophylactic medications in migraine patients.
The data on migraine patients who underwent PNB in our clinic between November 2019 and January 2022 were retrospectively reviewed. Blocks of the greater occipital nerve (GON), lesser occipital nerve (LON) and supraorbital nerve (SON) were performed upon admission and in the second week.
The study included 116 patients. While 21 out of 39 episodic migraine (EM) patients continued to use prophylactic medications, 18 were followed up with PNB alone. While 49 out of 77 chronic migraine (CM) patients continued to use prophylactic medications, 28 were followed up with PNB alone. Comparison of the admission and second-month data of the patients who only underwent PNB and those who continued the drug treatment together with PNB in both the EM and the CM group showed that the number of days with pain, number of analgesics taken and scores on the Visual Analog Scale (VAS) and the Migraine Disability Assessment (MIDAS) were significantly reduced in both groups ( < 0.01). Comparison of the second-month data of the patients followed up with PNB alone and those followed up with PNB together with prophylactic medications showed that there was no significant difference between the EM and CM patients ( > 0.05).
Bilateral GON, LON and SON block with lidocaine injection seems to be an effective treatment on its own, without the need for prophylactic medications, in both EM and CM patients during a two-month follow-up.
外周神经阻滞(PNB)通常用于对药物治疗有抵抗的偏头痛患者。
比较单独行 PNB 与 PNB 联合预防性药物治疗偏头痛的疗效。
回顾性分析 2019 年 11 月至 2022 年 1 月在我院行 PNB 的偏头痛患者的临床资料。入院时和第 2 周行枕大神经(GON)、枕小神经(LON)和眶上神经(SON)阻滞。
共纳入 116 例患者。39 例发作性偏头痛(EM)患者中,21 例继续使用预防性药物,18 例单独接受 PNB 治疗;77 例慢性偏头痛(CM)患者中,49 例继续使用预防性药物,28 例单独接受 PNB 治疗。单独行 PNB 治疗的 EM 和 CM 患者的入院时和第 2 个月的各项数据比较显示,两组疼痛天数、止痛药使用次数、视觉模拟评分(VAS)和偏头痛残疾评估量表(MIDAS)评分均显著降低(均 P<0.01);单独行 PNB 治疗的 CM 患者与联合使用预防性药物治疗的 CM 患者的第 2 个月数据比较显示,两组间差异无统计学意义(均 P>0.05)。
在 2 个月的随访期间,对于 EM 和 CM 患者,双侧 GON、LON 和 SON 利多卡因注射阻滞似乎是一种有效的治疗方法,无需预防性药物。