Division of Gastroenterology, Department of Pediatrics, David Geffen School of Medicine UCLA, 10833 Le Conte Avenue, MDCC 12-383, Los Angeles, CA 90095, USA.
New York-Presbyterian Department of Pharmacy, New York-Presbyterian Hospital/Komansky Children's Hospital, 1283 York Avenue, FL15, New York, NY 10065, USA.
Clin Perinatol. 2023 Sep;50(3):575-589. doi: 10.1016/j.clp.2023.04.012. Epub 2023 Jun 1.
Intravenous lipid emulsions (ILEs) are a source of nonprotein calories and fatty acids and help promote growth in preterm infants and infants with intestinal failure. An ILE dose and oil source determines its fatty acid, phytosterol, and vitamin E delivery. These factors play a role in the infant's risk for essential fatty acid deficiency and cholestasis, and help modulate inflammation, immunity, and organ development. This article reviews different ILEs and their constituents and their relationship with neonatal health.
静脉内脂肪乳剂 (ILE) 是提供非蛋白热量和脂肪酸的来源，有助于促进早产儿和肠衰竭婴儿的生长。ILE 的剂量和油源决定了其脂肪酸、植物固醇和维生素 E 的输送。这些因素在婴儿必需脂肪酸缺乏和胆汁淤积的风险中发挥作用，并有助于调节炎症、免疫和器官发育。本文综述了不同的 ILE 及其成分及其与新生儿健康的关系。
