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2
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本文引用的文献

1
Body composition after implementation of an enhanced parenteral nutrition protocol in the neonatal intensive care unit: a randomised pilot trial.在新生儿重症监护病房实施强化肠外营养方案后的身体成分:一项随机试点试验。
Ann Hum Biol. 2024 Feb;51(1):2306352. doi: 10.1080/03014460.2024.2306352. Epub 2024 Jan 31.
2
Early versus late administration of amino acids in preterm infants receiving parenteral nutrition.早产儿接受肠外营养时早期与晚期给予氨基酸的比较。
Cochrane Database Syst Rev. 2024 Jan 26;1(1):CD008771. doi: 10.1002/14651858.CD008771.pub3.
3
Effect of SMOF lipid emulsion on physical growth and extrauterine growth retardation in very preterm infants: Insights from a multicenter retrospective cohort study.SMOF脂质乳剂对极早产儿体格生长及宫外生长迟缓的影响:一项多中心回顾性队列研究的见解
Nutrition. 2023 Dec;116:112221. doi: 10.1016/j.nut.2023.112221. Epub 2023 Sep 11.
4
[Comparison of the impact of different fat emulsions on clinical outcomes in preterm infants with varying duration of parenteral nutrition: a randomized controlled multicenter study].[不同脂肪乳剂对不同肠外营养持续时间的早产儿临床结局影响的比较:一项随机对照多中心研究]
Zhongguo Dang Dai Er Ke Za Zhi. 2023;25(9):901-908. doi: 10.7499/j.issn.1008-8830.2303074.
5
Guidelines for parenteral nutrition in preterm infants: The American Society for Parenteral and Enteral Nutrition.早产儿肠外营养指南:美国肠外与肠内营养学会
JPEN J Parenter Enteral Nutr. 2023 Sep;47(7):830-858. doi: 10.1002/jpen.2550. Epub 2023 Aug 23.
6
Parenteral Nutrition in the Neonatal Intensive Care Unit: Intravenous Lipid Emulsions.新生儿重症监护病房的肠外营养:静脉内脂肪乳剂。
Clin Perinatol. 2023 Sep;50(3):575-589. doi: 10.1016/j.clp.2023.04.012. Epub 2023 Jun 1.
7
Carnitine supplementation increases serum concentrations of free carnitine and total acylcarnitine in preterm neonates: A retrospective cohort study.左旋肉碱补充可增加早产儿血清游离肉碱和总酰基肉碱浓度:一项回顾性队列研究。
JPEN J Parenter Enteral Nutr. 2023 Aug;47(6):746-753. doi: 10.1002/jpen.2535. Epub 2023 Jul 16.
8
Analysis of risk factors for parenteral nutrition-associated cholestasis in preterm infants: a multicenter observational study.早产儿肠外营养相关性胆汁淤积的危险因素分析:一项多中心观察性研究。
BMC Pediatr. 2023 May 20;23(1):250. doi: 10.1186/s12887-023-04068-0.
9
Effects of mixed oil emulsion on short-term clinical outcomes in premature infants: A prospective, multicenter, randomized controlled trial.混合油乳剂对早产儿短期临床结局的影响:一项前瞻性、多中心、随机对照临床试验。
Eur J Clin Nutr. 2023 Aug;77(8):823-832. doi: 10.1038/s41430-023-01288-6. Epub 2023 May 3.
10
Which birth weight threshold to start parenteral nutrition? A single center experience.开始肠外营养的出生体重阈值是多少?一项单中心经验。
Eur J Clin Nutr. 2023 Apr;77(4):474-480. doi: 10.1038/s41430-022-01257-5. Epub 2023 Jan 10.

《新生儿肠外营养管理专家共识(2025年)》

[Expert consensus on parenteral nutrition management in neonates (2025)].

出版信息

Zhongguo Dang Dai Er Ke Za Zhi. 2025 Mar 15;27(3):247-261. doi: 10.7499/j.issn.1008-8830.2411156.

DOI:10.7499/j.issn.1008-8830.2411156
PMID:40105069
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11928041/
Abstract

Parenteral nutrition (PN) is widely utilized in the field of neonatology and is a critical life-saving intervention for critically ill neonates or preterm infants who cannot meet their energy and nutrient needs through enteral feeding. To further standardize and optimize the clinical management of PN, this consensus was developed by a working group based on relevant research progress both domestically and internationally. Employing the Grading of Recommendations Assessment, Development and Evaluation, the consensus presents 24 recommendations covering seven aspects of PN: indications, administration routes, energy, fluid volume, composition of nutritional solutions, timing of cessation, and monitoring. The aim is to provide guidance for relevant practitioners in PN management to improve the short-term and long-term outcomes for neonates.

摘要

肠外营养(PN)在新生儿科领域被广泛应用,对于那些无法通过肠内喂养满足能量和营养需求的危重新生儿或早产儿而言,它是一项关键的挽救生命的干预措施。为进一步规范和优化PN的临床管理,一个工作组依据国内外相关研究进展制定了本共识。该共识采用推荐意见分级评估、制定与评价(GRADE)方法,提出了涵盖PN七个方面的24条推荐意见:适应证、给药途径、能量、液体量、营养溶液成分、停用时机及监测。目的是为PN管理的相关从业者提供指导,以改善新生儿的短期和长期预后。