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肠坏死性小肠结肠炎后肠内营养的现状、挑战和建议。

Current Practices, Challenges, and Recommendations in Enteral Nutrition After Necrotizing Enterocolitis.

机构信息

Department of Pediatrics, Section of Neonatology, Baylor College of Medicine, Texas Children's Hospital, Houston, TX, USA.

Wake Forest School of Medicine, Brenner Children's Hospital, Atrium Health Wake Forest Baptist, Winston-Salem, NC, USA.

出版信息

Clin Perinatol. 2023 Sep;50(3):683-698. doi: 10.1016/j.clp.2023.04.009. Epub 2023 May 26.

DOI:10.1016/j.clp.2023.04.009
PMID:37536772
Abstract

Necrotizing enterocolitis (NEC) is a neonatal disease with high mortality and morbidity. There is a lack of evidence-based recommendations on nutritional rehabilitation following NEC, and much of the current practice is guided by institutional policies and expert opinions. After a diagnosis of NEC, infants are exposed to an extended period of bowel rest and a prolonged course of antibiotics. Recognizing the patient characteristics that predict nutritional tolerance, early initiation of enteral nutrition, minimizing periods of bowel rest and antibiotic exposure, and standardization of dietary practices are the mainstay of post-NEC nutrition.

摘要

新生儿坏死性小肠结肠炎(NEC)是一种具有高死亡率和发病率的新生儿疾病。目前,针对 NEC 后的营养康复尚无循证推荐意见,许多现行实践是由机构政策和专家意见指导的。在 NEC 确诊后,患儿需要经历长时间的肠道休息和长时间的抗生素疗程。识别出可预测患儿营养耐受情况的特征,尽早开始肠内营养,尽量减少肠道休息和抗生素暴露时间,并规范饮食实践,这些是 NEC 后营养的主要内容。

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