辐照葡萄糖对小鼠体细胞和生殖细胞无致断裂效应。
Lack of clastogenic effects of irradiated glucose in somatic and germ cells of mice.
作者信息
Varma M B, Rao K P, Nandan S D, Rao M S
出版信息
Mutat Res. 1986 Jan-Feb;169(1-2):55-9. doi: 10.1016/0165-1218(86)90019-4.
PMID:3753743
Abstract
The clastogenic ability of irradiated glucose was evaluated using the micronucleus test in bone marrow cells and the chromosomal aberration assay in the spermatogonial cells of mice. Glucose was irradiated with 0.2, 2.0, 20 and 50 kGy of gamma-rays and administered to mice for various periods. No evidence of mutagenic effects was observed in somatic or germ cells.
摘要
使用小鼠骨髓细胞微核试验和精原细胞染色体畸变试验评估辐照葡萄糖的致断裂能力。用0.2、2.0、20和50千戈瑞的γ射线辐照葡萄糖，并在不同时间段给予小鼠。在体细胞或生殖细胞中未观察到诱变作用的证据。
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