Department of Anesthesiology, University Medical Center Göttingen, Robert-Koch-Strasse 40, 37075, Göttingen, Germany.
Department of Anesthesiology, Intensive care, Emergency and Pain medicine, Asklepios Clinic Altona, Paul-Ehrlich-Strasse 1, 22763, Hamburg, Germany.
BMC Emerg Med. 2023 Aug 4;23(1):83. doi: 10.1186/s12873-023-00850-6.
Accidental hypothermia is a manifest problem during the rescue of entrapped victims and results in different subsequent problems as coagulopathy and wound infection. Different warming methods are available for the preclinicial use. However, their effectiveness has hardly been evaluated.
In a first step a survey among German fire brigades was performed with questions about the most used warming methods. In a second step two crossover studies were conducted. In each study two different warming method were compared with forced air warming - which is the most frequently used and highly effective warming method in operation rooms (Study A: halogen floodlight vs. forced air warming; Study B: forced air warming vs. fleece blanket). In both studies healthy volunteers (Study A: 30 volunteers, Study B: 32 volunteers) were sitting 60 min in a cold store. In the first 21 min there was no subject warming. Afterwards the different warming methods were initiated. Every 3 min parameters like skin temperature, core body temperature and cold perception on a 10-point numeric rating scale were recorded. Linear mixed models were fitted for each parameter to check for differences in temperature trajectories and cold perception with regard to the different warming methods.
One hundred fifty-one German fire brigades responded to the survey. The most frequently used warming methods were different rescue blankets (gold/silver, wool) and work light (halogen floodlights). Both studies (A and B) showed significantly (p < 0.05) higher values in mean skin temperature, mean body temperature and total body heat for the forced air warming methods compared to halogen floodlight respectively fleece blanket shortly after warming initiation. In contrast, values for the cold perception were significantly lower (less unpleasant cold perception) during the phase the forced air warming methods were used, compared to the fleece blanket or the halogen floodlight was used.
Forced air warming methods used under the standardised experimental setting are an effective method to keep patients warm during technical rescue. Halogen floodlight has an insufficient effect on the patient's heat preservation. In healthy subjects, fleece blankets will stop heat loss but will not correct heat that has already been lost.
The studies were registered retrospectively on 14/02/2022 on the German Clinical Trials registry (DRKS) with the number DRKS00028079.
意外低体温是救援被困受害者时出现的明显问题,会导致凝血功能障碍和伤口感染等后续问题。有不同的升温方法可用于临床前使用。然而,它们的有效性几乎没有得到评估。
首先,对德国消防队进行了一项调查,询问他们最常用的升温方法。然后进行了两项交叉研究。在每项研究中,都将两种不同的升温方法与强制空气升温进行了比较——这是手术室中最常用且非常有效的升温方法(研究 A:卤素探照灯与强制空气升温;研究 B:强制空气升温与毛毯)。在两项研究中,健康志愿者(研究 A:30 名志愿者,研究 B:32 名志愿者)都在寒冷的仓库中坐 60 分钟。在前 21 分钟,志愿者没有进行体温升温。之后,启动了不同的升温方法。每 3 分钟记录一次皮肤温度、核心体温和 10 分制数字评分量表上的冷感等参数。对每个参数进行线性混合模型拟合,以检查不同升温方法对温度轨迹和冷感的差异。
有 151 个德国消防队对调查做出了回应。最常用的升温方法是不同的救援毯(金/银、羊毛)和工作灯(卤素探照灯)。两项研究(A 和 B)均显示,在升温启动后不久,与卤素探照灯或毛毯相比,强制空气升温方法的平均皮肤温度、平均体温和全身热量的数值显著更高(p<0.05)。相比之下,在使用强制空气升温方法的阶段,冷感的数值显著更低(冷感不那么不愉快)。
在标准化实验条件下使用的强制空气升温方法是保持技术救援中患者温暖的有效方法。卤素探照灯对患者的保暖效果不足。在健康受试者中,毛毯可以阻止热量流失,但不能纠正已经流失的热量。
该研究于 2022 年 2 月 14 日在德国临床试验注册中心(DRKS)以 DRKS00028079 号进行了回顾性注册。