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用于比较核苷酸和氨基酸残基序列的MTX计算机程序包。

The MTX package of computer programmes for the comparison of sequences of nucleotides and amino acid residues.

作者信息

Reisner A H, Bucholtz C A

出版信息

Nucleic Acids Res. 1986 Jan 10;14(1):233-8. doi: 10.1093/nar/14.1.233.

Abstract

A suite of some dozen programmes written in FORTRAN77 to run on VAX computers using the VMS operating system, and which utilizes a Digital Command Language (DCL) shell to allow it to be menu driven has been in use at the Division of Molecular Biology for about nine months. The package allows the user to obtain both dot matrix and line matrix plots, find and output specific regions of similarity and compute statistics for randomly generated sequences. In all these cases the user may specify either a maximum number of gaps in the match that will be tolerated or a minimum percentage similarity allowable for a match to be registered. The system allows the user to create a batch job for any of these analyses; so, for example, a number of line matrix plots can be specified from a remote alpha-numeric terminal which can be plotted later at a graphics terminal. In addition, computation of quasi-correlation statistics (Qr) for nucleotide sequences or correlation statistics (r) for amino acid residue sequences may be computed. Help facilities and documentation including examples are provided.

摘要

有一套大约十二个用FORTRAN77编写的程序,用于在使用VMS操作系统的VAX计算机上运行,并且利用数字命令语言(DCL)外壳使其能够通过菜单驱动,分子生物学部门已经使用这套程序大约九个月了。该软件包允许用户获得点阵图和线阵图,找到并输出特定的相似区域,并为随机生成的序列计算统计数据。在所有这些情况下,用户可以指定匹配中允许容忍的最大间隙数,或者允许注册匹配的最小相似百分比。该系统允许用户为这些分析中的任何一种创建批处理作业;例如,可以从远程字母数字终端指定多个线阵图,稍后可以在图形终端上绘制。此外,还可以计算核苷酸序列的准相关统计量(Qr)或氨基酸残基序列的相关统计量(r)。提供了帮助设施和包括示例的文档。

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