Office of Global Affairs, Thomas Jefferson University, Philadelphia, Pennsylvania, USA.
Int J Gynaecol Obstet. 2023 Aug;162 Suppl 2:78-82. doi: 10.1002/ijgo.14950.
Over 50% of pregnant women are anemic and the majority of these are iron deficient. Micronutrient deficiency, the symptom of heavy menstrual bleeding in nonpregnant individuals, and loss of blood associated with pregnancy and obstetric delivery contribute to iron deficiency (ID). Poor outcomes with low maternal iron can affect not only the pregnancy but can also have major bearings on the offspring. Correction of ID and iron deficiency anemia (IDA) in pregnant and prepregnant populations with single-dose intravenous iron supplementation may offer improved outcomes. A harmonization process that incorporates all major randomized controlled trials studying the use of single-dose IV iron compared with oral iron may suggest actions for changing the global trajectory of ID/IDA for women and girls of reproductive age.
超过 50%的孕妇贫血，其中大多数是缺铁性贫血。微量营养素缺乏、非妊娠个体月经过多的症状以及与妊娠和产科分娩相关的失血都会导致缺铁（ID）。母体铁含量低会导致不良后果，不仅会影响妊娠，还会对后代产生重大影响。通过单次静脉铁补充剂纠正妊娠和备孕人群的 ID 和缺铁性贫血（IDA），可能会改善结局。纳入所有主要随机对照试验的协调过程，研究单次静脉铁与口服铁的比较，可能会为改变育龄妇女和女孩 ID/IDA 的全球轨迹提供行动建议。
