Ha-Wissel Linh, Kröger Lasse, Langan Ewan A, Kahle Birgit, Boch Katharina
Department of Dermatology University of Lübeck Lübeck Germany.
Comprehensive Center for Inflammation Medicine University-Hospital Schleswig-Holstein Lübeck Germany.
Skin Health Dis. 2023 Mar 19;3(4):e230. doi: 10.1002/ski2.230. eCollection 2023 Aug.
Granuloma faciale is a rare, benign skin disease characterised by solitary or multiple papules, plaques or nodules, most often occurring on the face. The skin disorder is often associated with exacerbations and remissions; spontaneous resolution seldom occurs. The treatment of granuloma faciale is challenging. Various topical and systemic treatments, but also surgical and laser therapies have been administered. A spatially confined thermal destruction of the tissue is achieved by strong absorption of haemoglobin at 585 nm wavelength. Of note, none of the presently available therapeutic interventions are particularly successful. Moreover, Granuloma faciale has the tendency to recur after treatment. Here, we present a male patient with a treatment refractory Granuloma faciale on the right cheek who was successfully treated with the combination of surgery and pulsed-dye laser therapy. Besides the good aesthetic outcome, remission was maintained after almost 1 year of follow-up.
面部肉芽肿是一种罕见的良性皮肤病,其特征为单个或多个丘疹、斑块或结节,最常发生于面部。这种皮肤疾病常伴有病情加重和缓解;很少会自发消退。面部肉芽肿的治疗具有挑战性。已采用了各种局部和全身治疗方法,还有手术和激光疗法。通过血红蛋白在585纳米波长处的强烈吸收实现对组织的空间局限性热破坏。值得注意的是,目前可用的治疗干预措施均未取得特别显著的成功。此外,面部肉芽肿在治疗后有复发的倾向。在此,我们报告一名右侧脸颊患有难治性面部肉芽肿的男性患者,该患者通过手术和脉冲染料激光疗法联合治疗获得成功。除了良好的美学效果外,随访近1年后病情仍保持缓解。