Mamfaluti Teuku, Firdausa Sarah, Siregar Masra Lena, Hasan Maryatun, Murdia Murdia
Department of Internal Medicine, Dr. Zainoel Abidin Hospital, Banda Aceh, Indonesia.
Department of Internal Medicine, Faculty of Medicine, Universitas Syiah Kuala, Banda Aceh, Indonesia.
Heliyon. 2023 Jul 14;9(7):e18293. doi: 10.1016/j.heliyon.2023.e18293. eCollection 2023 Jul.
AIDS patients are more susceptible to opportunistic diseases, such as toxoplasma encephalitis, because of weakened immune systems. Toxoplasma encephalitis manifests as a severe neurological crisis in HIV patients. The standard initial treatments are sulfadiazine and pyrimethamine. This case presents an HIV patient treated with an alternative regimen for toxoplasma encephalitis.
A young Acehnese man, 32 years old, arrived at the emergency unit after complaining of a general seizure 2 hours before arrival. He has a history of a two-week fever and white patches on his tongue and oral cavity. The result of the HIV test was positive, and after a thorough examination, he was diagnosed with toxoplasma encephalitis. The patient was given cotrimoxazole 960 mg twice daily and clindamycin 600 mg four times daily as an alternative treatment. Clinical improvement was reported after six weeks of therapy.
A case of toxoplasma encephalitis was reported. The first-line treatment for toxoplasma encephalitis is pyrimethamine and sulfadiazine; however, the patient was treated with cotrimoxazole and clindamycin as an alternative treatment. Clinical improvement was used to assess the success of therapy. Cotrimoxazole and clindamycin can be utilized as alternative regiment therapy if the first-line treatment option is unavailable.
艾滋病患者由于免疫系统减弱，更容易感染机会性疾病，如弓形虫脑炎。弓形虫脑炎在艾滋病患者中表现为严重的神经危机。标准的初始治疗方法是磺胺嘧啶和乙胺嘧啶。本病例介绍了一名接受弓形虫脑炎替代治疗方案的艾滋病患者。
一名32岁的年轻亚齐男子在到达前2小时抱怨全身癫痫发作后抵达急诊室。他有两周发热史，舌头和口腔有白色斑块。艾滋病毒检测结果呈阳性，经过全面检查，他被诊断为弓形虫脑炎。患者接受了每日两次960毫克复方新诺明和每日四次600毫克克林霉素的替代治疗。治疗六周后报告临床症状有所改善。
报告了一例弓形虫脑炎病例。弓形虫脑炎的一线治疗药物是乙胺嘧啶和磺胺嘧啶；然而，该患者接受了复方新诺明和克林霉素作为替代治疗。通过临床症状改善来评估治疗的成功与否。如果一线治疗方案不可用，复方新诺明和克林霉素可作为替代治疗方案。
