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[已撤回]下一代紫杉烷SB-T-121205可增强MCF-7/PTX细胞的凋亡并抑制其迁移/侵袭。

[Retracted] SB-T-121205, a next-generation taxane, enhances apoptosis and inhibits migration/invasion in MCF-7/PTX cells.

作者信息

Zheng Xiaowei, Wang Changwei, Xing Yuanming, Chen Siying, Meng Ti, You Haisheng, Ojima Iwao, Dong Yalin

机构信息

Department of Pharmacy, The First Affiliated Hospital of Xi'an Jiaotong University, Xi'an, Shaanxi 710061, P.R. China.

Department of Chemistry, Stony Brook University - State University of New York, Stony Brook, NY 11794-3400, USA.

出版信息

Int J Oncol. 2023 Sep;63(3). doi: 10.3892/ijo.2023.5552. Epub 2023 Aug 4.

DOI:10.3892/ijo.2023.5552
PMID:37539753
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10552727/
Abstract

Following the publication of this paper, and subsequently to a corrigendum that was published to take account of errors that had been made concerning the Transwell invasion assay data in Fig. 4B (doi: 10.3892/ijo.2022.5463), it was drawn to the Editor's attention by a concerned reader that the western blots shown in Figs. 3C and 6B shared the same control data; moreover, potential anomalies were identified in the flow cytometric plots shown in Fig. 2A. Although the authors proposed to publish a corrigendum to account for these errors, including new data after having performed certain of the experiments again, given the number of problems that have been identified concerning the assembly of various of the figures in the published paper, the Editor of has decided not to publish a further corrigendum, and has, in fact, determined that this paper should be retracted from the Journal on account of an overall lack of confidence in the originally presented data. The Editor apologizes to the readership for any inconvenience caused. [International Journal of Oncology 50: 893-902, 2017; DOI: 10.3892/ijo.2017.3871].

摘要

在本文发表之后,以及随后为修正图4B中Transwell侵袭实验数据的错误而发表了一份勘误表(doi: 10.3892/ijo.2022.5463)之后,一位关切的读者提醒编辑注意,图3C和6B中所示的蛋白质免疫印迹共享相同的对照数据;此外,在图2A所示的流式细胞仪图中发现了潜在异常。尽管作者提议发表一份勘误表来解释这些错误,包括在再次进行某些实验后提供新数据,但鉴于已发现已发表论文中各种图的组装存在诸多问题,《国际肿瘤学杂志》的编辑决定不再发表进一步的勘误表,事实上,已决定因对最初呈现的数据总体缺乏信心而将本文从该期刊撤回。编辑就造成的任何不便向读者致歉。[《国际肿瘤学杂志》50: 893 - 902, 2017; DOI: 10.3892/ijo.2017.3871]

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