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[已撤回] NR4A1诱导人胃癌细胞系对TNFα介导的凋亡敏感性增加与JNK/帕金依赖性线粒体自噬的抑制有关。

[Retracted] NR4A1‑induced increase in the sensitivity of a human gastric cancer line to TNFα‑mediated apoptosis is associated with the inhibition of JNK/Parkin‑dependent mitophagy.

作者信息

Yan Hongzhu, Xiao Feng, Zou Jue, Qiu Chengmin, Sun Weiwei, Gu Minmin, Zhang Li

机构信息

Department of Pathology, Seventh People's Hospital of Shanghai University of TCM, Shanghai 200137, P.R. China.

Department of Pathology, Songjiang Hospital Affiliated to Τhe First People's Hospital, Shanghai Jiao Tong University, Shanghai 201600, P.R. China.

出版信息

Int J Oncol. 2024 Aug;65(2). doi: 10.3892/ijo.2024.5666. Epub 2024 Jun 28.

DOI:10.3892/ijo.2024.5666
PMID:38940348
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11251739/
Abstract

Following the publication of this paper, it was drawn to the Editor's attention by a concerned reader that certain of the data shown in Figs. 2A and 4F were strikingly similar to data appearing in different form in other articles written by different authors at different research institutes that were submitted to their respective journals at around the same time; moreover, the same data had apparently been included in the western blots featured in Fig. 5A to show the Parkin and mito‑LCIII protein bands. As it was not clear what had been the original venue for the submission of the strikingly similar data here, the Editor requested that the authors send to us all the raw data underlying the affected figures; however, the authors were not able to comply with this request at the time of asking. Given that the authors were unable to provide the supporting data as requested, the Editor of has decided that this paper should be retracted from the Journal on account of a lack of confidence in the presented data. The authors were asked for an explanation to account for these concerns, but the Editorial Office did not receive a satisfactory reply. The Editor apologizes to the readership for any inconvenience caused. [International Journal of Oncology 52: 367‑378, 2018; DOI: 10.3892/ijo.2017.4216].

摘要

在本文发表后,一位关注此事的读者提醒编辑注意,图2A和4F中所示的某些数据与不同研究机构的不同作者在大约同一时间提交给各自期刊的其他文章中以不同形式出现的数据惊人地相似;此外,相同的数据显然被包含在图5A的蛋白质免疫印迹中以显示帕金蛋白和线粒体LCIII蛋白条带。由于不清楚此处惊人相似数据的原始提交出处,编辑要求作者向我们发送所有受影响图的原始数据;然而,作者在被要求时无法遵守这一要求。鉴于作者无法按要求提供支持数据,《国际肿瘤学杂志》的编辑决定,由于对所呈现的数据缺乏信心,应从该期刊撤回本文。已要求作者对这些问题作出解释,但编辑部未收到令人满意的答复。编辑就由此造成的不便向读者致歉。[《国际肿瘤学杂志》52: 367 - 378, 2018;DOI: 10.3892/ijo.2017.4216]

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