Deland M P, Lewis D, Cunningham P R, Dewey D W
Aust Vet J. 1986 Jan;63(1):1-3. doi: 10.1111/j.1751-0813.1986.tb02860.x.
Oxidised copper wire particles (OCWP) were given per os to cattle as an alternative to subcutaneous copper glycinate injections. OCWP were recovered from the stomachs of cattle slaughtered 3 months after treatment. OCWP (50g) treatment resulted in sustained higher plasma copper concentrations than subcutaneous injections of copper glycinate. OCWP given at high doses (300g) raised liver copper concentrations to 16 mmol/kg without clinical effects. It is concluded that OCWP could be a practical alternative to current injection methods of copper therapy.
将氧化铜线颗粒（OCWP）经口给予牛，作为皮下注射甘氨酸铜的替代方法。在治疗3个月后屠宰的牛的胃中回收了OCWP。给予OCWP（50克）治疗后，血浆铜浓度持续高于皮下注射甘氨酸铜。高剂量（300克）给予OCWP可使肝脏铜浓度升高至16毫摩尔/千克，且无临床影响。结论是，OCWP可能是目前铜治疗注射方法的一种实用替代方法。
