Kazarian P A, Karagezian K G
Biull Eksp Biol Med. 1986 Mar;101(3):296-8.
Glycerokinase, glycerophosphate dehydrogenase, glycerophosphate acyltransferase activity, glycerophosphate, dioxiacetonphosphate level and in vivo incorporation of (U-14C)-glucose into the lung phospholipid structure were studied in normal rats and in conditions of chronic bronchopulmonary inflammation. The inhibition of glycerokinase and glycolytic ways of glycerophosphate formation was demonstrated. The data obtained have shown that glucose incorporation into phosphatidyl cholines, phosphatidyl glycerols and phosphatidyl ethanolamines was decreased, while the incorporation of radioactivity into the sphingomyelins and lysophosphatidyl cholines was significantly activated.
在正常大鼠以及慢性支气管肺炎状态下，研究了甘油激酶、甘油磷酸脱氢酶、甘油磷酸酰基转移酶活性、甘油磷酸、二羟丙酮磷酸水平以及（U-14C）-葡萄糖在体内掺入肺磷脂结构的情况。结果表明甘油激酶以及甘油磷酸形成的糖酵解途径受到抑制。所获数据显示，葡萄糖掺入磷脂酰胆碱、磷脂酰甘油和磷脂酰乙醇胺的量减少，而放射性掺入鞘磷脂和溶血磷脂酰胆碱的量则显著增加。
