Cao Honggang, Shi Hongtai, Zhao Miaomiao, Liu Zhenhua, Qian Jun
Department of Oncology, The Sixth Affiliated Hospital of Nantong University, Yancheng Third People's Hospital, 75 Juchang Street, Yancheng, 224005, China.
Department of Radiation Oncology, The Sixth Affiliated Hospital of Nantong University, Yancheng Third People's Hospital, 75 Juchang Street, Yancheng, 224005, China.
Discov Oncol. 2023 Aug 4;14(1):143. doi: 10.1007/s12672-023-00763-7.
The prognostic indexes based on the combination of preoperative fibrinogen and systemic inflammatory indexes may have greater predictive value in esophageal squamous cell carcinoma (ESCC). It was found that the predictive ability of F-NLR was more valuable than other systemic inflammatory indexes. The preoperative F-NLR score was closely related to the TNM stage, and could be used as an important independent prognostic index for patients with ESCC. Then the nomogram model constructed by F-NLR and TNM stage had higher prognostic ability than that of AJCC stage for ESCC patients. Preoperative F-NLR is a new independent prognostic index and a potential marker for treatment response monitoring in patients with ESCC.
基于术前纤维蛋白原与全身炎症指标联合的预后指标在食管鳞状细胞癌（ESCC）中可能具有更大的预测价值。研究发现，F-NLR的预测能力比其他全身炎症指标更有价值。术前F-NLR评分与TNM分期密切相关，可作为ESCC患者重要的独立预后指标。由F-NLR和TNM分期构建的列线图模型对ESCC患者的预后评估能力高于AJCC分期。术前F-NLR是ESCC患者新的独立预后指标及治疗反应监测的潜在标志物。
