犬肾扫描剂N-琥珀酰去铁胺B的评估
Evaluation of the renal scanning agent N-succinyldesferrioxamine B in dogs.
作者信息
Herscheid J D, Isaacs H, de Jong R B, Hoekstra A
出版信息
Eur J Nucl Med. 1986;11(9):363-4. doi: 10.1007/BF00253303.
PMID:3754209
Abstract
The mechanism of the excretion of 67 Ga-N-succinyldesferrioxamine B (SDF) was investigated in five healthy dogs. Comparison of the SDF clearance rates for whole blood and plasma as well as SDF renograms with those of 131 I-o-iodohippuric acid (OIH) and 111In-diethylenetriamine-pentaacetic acid (DTPA) revealed that SDF is cleared by glomerular filtration and not by an active tubular transport mechanism.
摘要
在五只健康犬中研究了67Ga-N-琥珀酰去铁胺B（SDF）的排泄机制。将全血和血浆的SDF清除率以及SDF肾图与131I-邻碘马尿酸（OIH）和111In-二乙三胺五乙酸（DTPA）的清除率及肾图进行比较，结果显示SDF是通过肾小球滤过清除，而非通过主动肾小管转运机制清除。
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