血红蛋白姬路或β140（H18）丙氨酸----天冬氨酸。一种轻度不稳定的血红蛋白，其β氨基末端糖化增加。
Hb Himeji or beta 140 (H18) Ala----Asp. A slightly unstable hemoglobin with increased beta N-terminal glycation.
作者信息
Ohba Y, Miyaji T, Murakami M, Kadowaki S, Fujita T, Oimomi M, Hatanaka H, Ishikawa K, Baba S, Hitaka K
出版信息
Hemoglobin. 1986;10(2):109-25. doi: 10.3109/03630268609046438.
A fast-moving abnormal hemoglobin found in a diabetic patient was identified as beta 140 (H18) Ala----Asp. It comprised about 40% of the total hemoglobin. The beta N-terminal glycation in the abnormal hemoglobin was estimated to be 3 times as much as that in Hb A in the same blood sample. The abnormal hemoglobin was slightly unstable. Oxygen affinity of the stripped hemoglobin was decreased, but that of red cells from the carrier was slightly higher than normal because of the reduced effect of 2,3-diphosphoglycerate.
在一名糖尿病患者中发现的一种快速移动的异常血红蛋白被鉴定为β140（H18）丙氨酸→天冬氨酸。它约占总血红蛋白的40%。在同一血样中，异常血红蛋白的β氨基末端糖基化程度估计是Hb A的3倍。这种异常血红蛋白略有不稳定。脱辅基血红蛋白的氧亲和力降低，但由于2,3-二磷酸甘油酸的作用减弱，携带者红细胞的氧亲和力略高于正常水平。
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