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采用 CT KUB 评估疑似肾绞痛患者的临床显著尿路阳性率。

Assessment of clinically significant urolithiasis positivity rate using CT KUB for suspected renal colic.

机构信息

Tallaght University Hospital, Dublin, Ireland.

出版信息

Ir J Med Sci. 2024 Apr;193(2):1009-1013. doi: 10.1007/s11845-023-03477-5. Epub 2023 Aug 5.

Abstract

BACKGROUND

Unenhanced low-dose computed tomography of the kidneys, ureter and bladder (CT KUB) is the gold standard diagnostic imaging modality in the assessment of suspected renal colic. As the radiation dose is not negligible, it is important to monitor the diagnostic yield of CT KUBs. The aim of this study is to evaluate the diagnostic yield of CT KUB studies performed for suspected renal colic in patients presenting to the emergency department.

METHODS

A retrospective review was performed of 500 patients who underwent CT KUB for suspected renal colic over a seven month period from June 2019 to January 2020. Clinical information and imaging was reviewed for each patient. Statistical analysis was performed using GraphPad Prism 8 (GraphPad Software, San Diego, CA, USA).

RESULTS

Forty-nine percent of patients in the series were female (248/500) and the mean age was 45. The positivity rate for obstructing ureteral calculus was 34% (169/500). Concerningly, there was a significantly lower positivity rate in females compared to males (19% versus 48%; p < 0.0001) which raises the issue of unnecessary radiation exposure to this cohort. In the 200 female patients who were negative for obstructing urolithiasis, the mean age was 43. Females also had a significantly higher rate of negative CT KUB (62% versus 37%; p < 0.0001) where no underlying alternative pathology was diagnosed.

CONCLUSIONS

Women are less likely than men to have obstructing urolithiasis on CT KUB for suspected renal colic. This difference is not accounted for by a higher rate of alternative diagnoses among female patients. The findings of this study should prompt clinicians to exercise caution when considering this imaging modality in this patient cohort.

摘要

背景

在疑似肾绞痛的评估中,未增强的低剂量肾脏、输尿管和膀胱 CT(CT KUB)是金标准诊断成像方式。由于辐射剂量不容忽视,因此监测 CT KUB 的诊断效果非常重要。本研究旨在评估在急诊科就诊的疑似肾绞痛患者中进行 CT KUB 的诊断效果。

方法

对 2019 年 6 月至 2020 年 1 月期间进行 CT KUB 检查的 500 例疑似肾绞痛患者进行回顾性分析。对每位患者的临床资料和影像学表现进行了回顾。使用 GraphPad Prism 8(GraphPad Software,San Diego,CA,USA)进行统计分析。

结果

本研究系列中 49%的患者为女性(248/500),平均年龄为 45 岁。梗阻性输尿管结石的阳性率为 34%(169/500)。值得注意的是,女性的阳性率明显低于男性(19%比 48%;p<0.0001),这表明该队列存在不必要的辐射暴露。在 200 例未发现梗阻性尿路结石的女性患者中,平均年龄为 43 岁。女性的 CT KUB 阴性率也明显更高(62%比 37%;p<0.0001),其中没有诊断出潜在的其他疾病。

结论

在疑似肾绞痛的 CT KUB 检查中,女性发生梗阻性尿路结石的可能性低于男性。这种差异不能用女性患者中替代诊断的更高发生率来解释。本研究的结果应促使临床医生在考虑该影像学方法时对该患者群体保持谨慎。

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