Abkiewicz C, Lomnitzer R, Rabson A R
S Afr Med J. 1979 Feb 24;55(8):285-7.
Forty patients who had previously experienced severe systemic reactions after a bee sting were desensitized using pure bee venom. A modified 'Rush' regimen was employed whereby patients received two injections a week and reached maximal desensitization in 5 weeks. Eleven patients have subsequently been stung again and have developed no generalized reaction. Although this form of desensitization is considered to be highly effective in protecting sensitive patients, both generalized and local side-effects were frequent. Maintenance desensitizing injections are required every month for an indefinite period. It is concluded that desensitization with pure been venom should be undertaken only in highly selected sensitive patients, and should be performed under strict control.
40名曾在被蜜蜂蜇伤后出现严重全身反应的患者用纯蜂毒进行了脱敏治疗。采用了一种改良的“快速”方案，即患者每周接受两次注射，并在5周内达到最大脱敏效果。随后有11名患者再次被蜇伤，未出现全身反应。尽管这种脱敏形式被认为在保护敏感患者方面非常有效，但全身和局部副作用都很常见。需要每月进行维持脱敏注射，时间不限。得出的结论是，仅应在经过严格挑选的敏感患者中使用纯蜂毒进行脱敏治疗，且应在严格控制下进行。
