阿扎尔队列研究中的多病共患模式及预测因素。
Patterns and Predictors of Multimorbidity in the Azar Cohort.
机构信息
Liver and Gastrointestinal Diseases Research Center, Tabriz University of Medical Sciences, Tabriz, Iran.
Nutrition Research Center, Tabriz University of Medical Sciences, Tabriz, Iran.
出版信息
Arch Iran Med. 2023 Jan 1;26(1):8-15. doi: 10.34172/aim.2023.02.
BACKGROUND
The co-existence of chronic diseases (CDs), a condition defined as multimorbidity (MM), is becoming a major public health issue. Therefore, we aimed to determine the patterns and predictors of MM in the Azar Cohort.
METHODS
We evaluated the prevalence of MM in 15,006 (35-70-year old) subjects of the Azar Cohort Study. MM was defined as the co-existence of two or more CDs. Data on the subjects' socioeconomic status, demographics, sleeping habits, and physical activity were collected using questionnaires.
RESULTS
The overall prevalence of MM was 28.1%. The most prevalent CDs, in decreasing order, were obesity, hypertension, depression, and diabetes. Obesity, depression, and diabetes were the most co-occurring CDs. The MM risk increased significantly with age, illiteracy, and in females. Also, the subjects within the lowest tertile of physical activity level (OR=1.89; 95% CI: 1.75-2.05) showed higher MM risk than those with the highest level of physical activity. Findings regarding current smoking status indicated that being an ex-smoker or smoker of other types of tobacco significantly increased the risk of MM.
CONCLUSION
The reduction of MM is possible by promoting public health from an early age among people of various socioeconomic conditions. It is vital to offer the necessary health support to the aging population of Iran.
背景
慢性病（CDs）的共存，即多种疾病共存（MM）的情况，正成为一个主要的公共卫生问题。因此，我们旨在确定 Azar 队列中 MM 的模式和预测因素。
方法
我们评估了 Azar 队列研究中 15006 名（35-70 岁）受试者的 MM 患病率。MM 被定义为两种或多种 CDs 的共存。使用问卷收集了受试者的社会经济状况、人口统计学、睡眠习惯和身体活动数据。
结果
MM 的总体患病率为 28.1%。最常见的 CD 按降序排列依次为肥胖、高血压、抑郁和糖尿病。肥胖、抑郁和糖尿病是最常见的共病 CD。MM 的风险随着年龄、文盲和女性而显著增加。此外，体力活动水平最低三分位的受试者（OR=1.89；95%CI：1.75-2.05）比最高水平的体力活动水平的受试者发生 MM 的风险更高。关于当前吸烟状况的研究结果表明，曾经吸烟或吸食其他类型的烟草会显著增加 MM 的风险。
结论
通过在不同社会经济条件下的人群中从早期开始促进公共卫生，可以降低 MM 的发生率。为伊朗的老年人口提供必要的健康支持至关重要。
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