Gerrard J W, Perelmutter L
Ann Allergy. 1986 Apr;56(4):351-4.
Nineteen children with IgE-mediated allergy associated with strongly positive prick skin tests and RASTs to peanut or cow's milk and/or egg were studied. Seventeen of the children had been breast fed, ten had been exclusively breast fed for a minimum of 5 months. Reactions to these foods occurred on first exposure to the food in all but one instance, suggesting that in 18 instances sensitization had occurred antenatally or via the breast. A retrospective inquiry indicated that most of the mothers had had a generous intake of the food(s) to which their children were sensitized, but mothers of sensitized children did not consume more of these foods than the mothers of non-sensitized children; moreover, avoidance of the foods (peanut in two instances and egg in one) did not ensure freedom from sensitization to peanut and/or egg. Breast feeding by itself cannot be guaranteed to protect against the development of food allergy.
对19名患有IgE介导过敏的儿童进行了研究，这些儿童的皮肤点刺试验和放射性变应原吸附试验对花生、牛奶和/或鸡蛋呈强阳性。其中17名儿童曾接受母乳喂养，10名儿童至少纯母乳喂养了5个月。除1例以外，所有儿童在首次接触这些食物时均出现反应，这表明在18例中，致敏发生在产前或通过母乳。一项回顾性调查表明，大多数母亲大量摄入了其孩子致敏的食物，但致敏儿童的母亲摄入这些食物的量并不比未致敏儿童的母亲多；此外，避免食用这些食物（2例花生和1例鸡蛋）并不能确保对花生和/或鸡蛋不致敏。母乳喂养本身并不能保证预防食物过敏的发生。
