di Sant'Agnese P A
Arch Pathol Lab Med. 1986 May;110(5):412-5.
Calcitoninlike immunoreactive and bombesinlike immunoreactive endocrine-paracrine (EP) cells are reported for the first time, to our knowledge, in the human prostate gland and urethra. While calcitoninlike immunoreactive and bombesinlike immunoreactive EP cells account for only a small percentage of the total number of prostatic and urethral EP cells, they underscore the heterogeneity and potential significance of these cells. Prostatic and urethral EP cells may well play an important role not only in the normal state but in such diverse pathologic conditions as infertility, nodular hyperplasia, and prostatic malignancy.
据我们所知，降钙素样免疫反应性和蛙皮素样免疫反应性内分泌旁分泌（EP）细胞首次在人类前列腺和尿道中被报道。虽然降钙素样免疫反应性和蛙皮素样免疫反应性EP细胞仅占前列腺和尿道EP细胞总数的一小部分，但它们突出了这些细胞的异质性和潜在重要性。前列腺和尿道EP细胞不仅在正常状态下，而且在诸如不育症、结节性增生和前列腺恶性肿瘤等多种病理状况下都很可能发挥重要作用。
