登革病毒蚊虫分离株与鸭源分离株在雏鸭和 3 周龄小鼠体内的致病性比较研究。
Comparative study of the pathogenicity of the mosquito origin strain and duck origin strain of Tembusu virus in ducklings and three-week-old mice.
机构信息
Institute of Preventive Veterinary Medicine, Sichuan Agricultural University, Chengdu, 611130, China.
Institute of Technology, University of Tartu, Tartu, 999148, Estonia.
出版信息
Virol Sin. 2023 Oct;38(5):827-831. doi: 10.1016/j.virs.2023.07.006. Epub 2023 Aug 5.
Abstract
• TMUV can infect Kunming mice by i.c., and the pathogenicity of mosquito TMUV is higher than that of duck TMUV. • TMUV can infect SPF ducklings by i.m., and the pathogenicity of duck TMUV is higher than that of mosquito TMUV. • SPF ducklings infected with mosquito TMUV did not produce viremia at 3, 5 and 7 dpi.
摘要
• TMUV 可通过脑内感染昆明系小鼠，且蚊源 TMUV 的致病性高于鸭源 TMUV。 • TMUV 可通过肌肉感染 SPF 雏鸭，且鸭源 TMUV 的致病性高于蚊源 TMUV。 • 感染蚊源 TMUV 的 SPF 雏鸭在 3、5 和 7 dpi 时均未产生血传病毒。
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