Department of Gynaecology, Affiliated Hospital of Nantong University, Medical School of Nantong University, Nantong, 226001, China.
Department of Oncology, Affifiliated Hospital of Nantong University, Medical School of Nantong University, Nantong, 226001, China.
Explore (NY). 2024 Jan-Feb;20(1):17-26. doi: 10.1016/j.explore.2023.06.015. Epub 2023 Jul 29.
Many women experience nausea and vomiting in early pregnancy. Regardless of the disease severity, it affects the work and life of pregnant women. However, drug treatment may potentially impact the foetus; thus, alternative safe and effective measures are essential. We aimed to evaluate the effect of acupressure, a non-drug treatment for nausea and vomiting, during pregnancy.
PubMed, EMBASE, Cochrane, Web of Science, CNKI, CBM, VIP, and Wanfang databases were searched using 'pregnancy', 'nausea', 'vomiting', and 'acupressure' as keywords. The search period was from database inception to 30 November 2022. Two researchers independently screened articles, extracted data, and used RevMan 5.4 software for statistical analysis.
We included 33 trials and 3 390 patients in this meta-analysis. Acupressure was effective for women with nausea and vomiting during pregnancy (odds ratio (OR)= 4.81, 95% confidence interval (CI) [3.47, 6.68]; p<0.0001); it significantly reduced the nausea score of the Rhodes index (mean square deviation (MD): -3.21, 95% CI [-4.85, -1.57], Z = 3.83, p = 0.0001), modified Pregnancy Unique Quantification of Emesis and Nausea score (MD: -2.18, 95% CI [-3.21, -1.15], Z = 4.15, p<0.0001), and hospital stay (OR=-3.27, 95% CI [-6.18, -0.36]; p = 0.03) and improved quality of life (MD: -14.06,95% CI [- 17.31, -10.18], Z = 8.48, p<0.00001). However, no significant difference was observed in nursing satisfaction and anxiety scores (OR=4.13, 95% CI [0.89, 19.15]; p = 0.07) (MD: -13.26,95% CI [-32.04,5.53], Z = 1.38, p = 0.17).
This meta-analysis provides evidence of a non-drug intervention for women with nausea and vomiting during pregnancy; acupressure effectively reduces nausea and vomiting during pregnancy.
许多女性在孕早期会出现恶心和呕吐。无论疾病严重程度如何，它都会影响孕妇的工作和生活。然而，药物治疗可能会对胎儿产生潜在影响；因此，需要采取替代的安全有效的措施。我们旨在评估非药物治疗方法——穴位按压对妊娠恶心和呕吐的效果。
使用“妊娠”、“恶心”、“呕吐”和“穴位按压”等关键词，检索 PubMed、EMBASE、Cochrane、Web of Science、CNKI、CBM、VIP 和万方数据库，检索时间为数据库建立至 2022 年 11 月 30 日。两位研究者独立筛选文献、提取数据，并使用 RevMan 5.4 软件进行统计分析。
本荟萃分析纳入了 33 项试验和 3390 名患者。穴位按压对妊娠恶心和呕吐的孕妇有效（比值比（OR）=4.81，95%置信区间（CI）[3.47，6.68]；p<0.0001）；它显著降低了 Rhodes 指数的恶心评分（均方根差（MD）：-3.21，95%CI[-4.85，-1.57]，Z=3.83，p=0.0001）、改良妊娠呕吐与恶心评分（MD：-2.18，95%CI[-3.21，-1.15]，Z=4.15，p<0.0001）和住院时间（OR=-3.27，95%CI[-6.18，-0.36]；p=0.03），并改善了生活质量（MD：-14.06，95%CI[-17.31，-10.18]，Z=8.48，p<0.00001）。然而，在护理满意度和焦虑评分方面，差异无统计学意义（OR=4.13，95%CI[0.89，19.15]；p=0.07）（MD：-13.26，95%CI[-32.04，5.53]，Z=1.38，p=0.17）。
本荟萃分析为妊娠恶心和呕吐的女性提供了一种非药物干预的证据，穴位按压可有效减轻妊娠恶心和呕吐。
