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印度正常体重中心性肥胖与高血压:2017-19 年 LASI 的横断面研究结果。

Normal weight central obesity and hypertension in India: Cross-sectional finding from LASI, 2017-19.

机构信息

Department of Health Research, International Institute of Health Management Research, New Delhi 110075, India.

Department of Anthropology, University of Delhi, Delhi 110007, India.

出版信息

Nutr Metab Cardiovasc Dis. 2023 Oct;33(10):1888-1898. doi: 10.1016/j.numecd.2023.06.022. Epub 2023 Jul 6.

Abstract

BACKGROUND AND AIM

The current public health guidelines for preventing and managing obesity still emphasize the importance of maintaining a normal Body Mass Index, while paying little attention to central obesity, which is common among the general population. Normal Weight Central Obesity (NWCO) is a less explored risk factor for hypertension in India. Therefore, this study aims to investigate the prevalence of NWCO and its association with hypertension in India.

METHODS AND RESULTS

The cross-sectional study used data from the Longitudinal Aging Study in India (LASI), 2017-19, which included 54,016 participants (22,438 men and 31,578 women). Hypertension was evaluated following the JNC-VIII guidelines for the detection, evaluation, and treatment of hypertension. Anthropometric measurements were taken to identify NWCO. The study found that NWCO was more prevalent among women (33.9%) than men (17.8%), while men had a higher prevalence of hypertension (47.6%) than women (43.8%). In India, the state of Haryana had the highest proportion of NWCO among men (26.4%), while Kerala had the highest proportion among women (39.1%). Binary logistic regression analysis showed that NWCO was significantly associated with an increased risk of hypertension. The odds ratio (aOR) was 1.57 (95% CI 1.45-1.67, p < 0.001) in men and 1.53 (95% CI 1.43-1.63, p < 0.001) in women, compared to normal-weight study participants.

CONCLUSIONS

The study emphasizes the importance of considering central obesity in individuals with a normal BMI when assessing cardiovascular risk, particularly for hypertension. State-specific data can help identify high-risk areas and facilitate targeted prevention and treatment strategies.

摘要

背景与目的

目前预防和管理肥胖的公共卫生指南仍然强调保持正常体重指数的重要性,而对普通人群中常见的中心性肥胖关注较少。正常体重中心性肥胖(NWCO)是印度高血压研究中一个较少被探讨的危险因素。因此,本研究旨在调查 NWCO 在印度的流行情况及其与高血压的关系。

方法与结果

本横断面研究使用了 2017-19 年印度纵向老龄化研究(LASI)的数据,共纳入 54016 名参与者(22438 名男性和 31578 名女性)。高血压的评估遵循 JNC-VIII 指南进行,用于检测、评估和治疗高血压。采用人体测量学测量来确定 NWCO。研究发现,NWCO 在女性中更为普遍(33.9%),而男性中高血压的患病率更高(47.6%)。在印度,哈里亚纳邦的男性 NWCO 比例最高(26.4%),而喀拉拉邦的女性 NWCO 比例最高(39.1%)。二元逻辑回归分析显示,NWCO 与高血压的风险增加显著相关。男性的比值比(aOR)为 1.57(95%CI 1.45-1.67,p<0.001),女性的 aOR 为 1.53(95%CI 1.43-1.63,p<0.001),与正常体重组相比。

结论

本研究强调在评估心血管风险时,特别是高血压,对于 BMI 正常的个体,应考虑中心性肥胖。特定州的数据可以帮助识别高风险地区,并促进有针对性的预防和治疗策略。

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