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尼日利亚南部一家三级医院 10 年卵巢病变的临床病理分析。

A 10-year clinicopathological analysis of ovarian lesions in a tertiary hospital in Southern Nigeria.

机构信息

Department of Obstetrics/Gynaecology, College of Health Sciences, University of Uyo.

Department of Pathology, College of Health Sciences, University of Uyo.

出版信息

Afr Health Sci. 2023 Mar;23(1):459-468. doi: 10.4314/ahs.v23i1.48.

DOI:10.4314/ahs.v23i1.48
PMID:37545925
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10398431/
Abstract

BACKGROUND

Ovarian tumours are the most lethal of all gynaecological cancers and they are usually diagnosed in advanced stages when the prognosis is very poor.

OBJECTIVE

To determine the pattern of ovarian lesions, their frequency, presentation, and associated clinical symptoms in Uyo, Nigeria.

METHODS

A 10-year retrospective study of all ovarian specimens that were surgically removed and histologically diagnosed.

RESULTS

The patients were between the ages of 5 and 73 years with median age of 34.1 years. Benign tumours occurred most commonly among the 20-39-year age group (31.3%) while malignant tumours were predominant among those aged 50-69 years (10.0%). Surface epithelial tumours (45.4%) were the most common neoplastic tumours while the mature cystic teratoma (33.2%) was the most common tumour overall. Surface epithelial malignancies accounted for 70.6% of all ovarian malignancies and the serous cyst adenocarcinoma (10.2%) was the most common surface epithelial tumour as well as the most common malignant tumour.

CONCLUSION

There has been an increase in the number of malignant ovarian specimens in our centre. Though surface epithelial tumours were the most common category of ovarian tumours, overall, the mature cystic teratoma was the most common tumour. Serous cyst adenocarcinoma was the most common surface epithelial tumour and the most common malignant tumour.

摘要

背景

卵巢肿瘤是所有妇科癌症中最致命的,通常在晚期诊断,预后非常差。

目的

确定尼日利亚 Uyo 地区卵巢病变的模式、其频率、表现以及相关的临床症状。

方法

对所有经手术切除和组织学诊断的卵巢标本进行了 10 年回顾性研究。

结果

患者年龄在 5 至 73 岁之间,中位数年龄为 34.1 岁。良性肿瘤最常见于 20-39 岁年龄组(31.3%),而恶性肿瘤则多见于 50-69 岁年龄组(10.0%)。表面上皮肿瘤(45.4%)是最常见的肿瘤,而成熟囊性畸胎瘤(33.2%)是最常见的肿瘤。表面上皮恶性肿瘤占所有卵巢恶性肿瘤的 70.6%,浆液性囊腺癌(10.2%)是最常见的表面上皮肿瘤,也是最常见的恶性肿瘤。

结论

我们中心的恶性卵巢标本数量有所增加。虽然表面上皮肿瘤是最常见的卵巢肿瘤类型,但总体而言,成熟囊性畸胎瘤是最常见的肿瘤。浆液性囊腺癌是最常见的表面上皮肿瘤,也是最常见的恶性肿瘤。

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BMC Womens Health. 2017 Apr 17;17(1):34. doi: 10.1186/s12905-017-0389-8.
2
Ovarian tumors among Nigerian females: A private practice experience in Benin-City, Nigeria.尼日利亚女性的卵巢肿瘤:尼日利亚贝宁城的私人执业经验
Adv Biomed Res. 2016 Mar 22;5:61. doi: 10.4103/2277-9175.179183. eCollection 2016.
3
Clinicopathologic features of ovarian neoplasms with emphasis on borderline ovarian tumors: an institutional perspective.卵巢肿瘤的临床病理特征,重点关注卵巢交界性肿瘤:来自一家机构的观点。
BMC Res Notes. 2016 Apr 6;9:205. doi: 10.1186/s13104-016-2015-5.
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Histologic pattern, bilaterality and clinical evaluation of 957 ovarian neoplasms: a 10-year study in a tertiary hospital of eastern India.957例卵巢肿瘤的组织学类型、双侧性及临床评估:印度东部一家三级医院的10年研究
J Cancer Res Ther. 2011 Oct-Dec;7(4):433-7. doi: 10.4103/0973-1482.92011.
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Niger Postgrad Med J. 2007 Jun;14(2):134-6.