Mondal Santosh Kumar, Banyopadhyay Ranjana, Nag Dipanwita Roy, Roychowdhury Suprio, Mondal Palash Kumar, Sinha Swapan Kumar
Department of Pathology, Medical College, Kolkata, India.
J Cancer Res Ther. 2011 Oct-Dec;7(4):433-7. doi: 10.4103/0973-1482.92011.
The aim was to study the distribution of morphological pattern of benign and malignant ovarian neoplasms in different age groups in eastern India and to determine the likelihood of bilateral involvement in different morphologic subtypes.
957 cases of ovarian tumors were studied over a period of 10 years (from January 2001 to December 2010).
Most of the benign tumors occurred between 20 and 40 years of age, while the malignant lesions presented commonly between 41 and 50 years. The most common histological types were serous cystadenoma (29.9%), followed by mature teratoma (15.9%) and mucinous cystadenoma (11.1%). Major proportion of malignant ovarian tumors was contributed by surface epithelial tumors (60.9%). Serous cystadenocarcinoma was the predominant malignant tumor (11.3%). Metastatic tumors were found to involve the bilateral ovaries in 72%, while 49.5% of malignant serous tumors were bilateral. Borderline serous tumors showed bilateral involvement more commonly (27.4%) than borderline mucinous tumors (15.7%). Most of the malignant tumors presented as stage III (60%) or stage II (20%) disease. The overall survival rate was 85% for stage I tumors, 65% for stage II, 30% for stage III and 15.5% for stage IV tumors.
We noted an earlier age at presentation of malignant tumors. Mature teratoma was found to be the second most common benign tumor (after serous cystadenoma). We also noted a lower percentage of endometrioid tumors. Lower number of stage IV tumors was noted, with a significant number of malignant ovarian tumors presenting at an earlier age.
研究印度东部不同年龄组良性和恶性卵巢肿瘤的形态学模式分布，并确定不同形态学亚型双侧受累的可能性。
在10年期间（从2001年1月至2010年12月）研究了957例卵巢肿瘤病例。
大多数良性肿瘤发生在20至40岁之间，而恶性病变通常出现在41至50岁之间。最常见的组织学类型是浆液性囊腺瘤（29.9%），其次是成熟畸胎瘤（15.9%）和黏液性囊腺瘤（11.1%）。恶性卵巢肿瘤的主要部分由表面上皮肿瘤构成（60.9%）。浆液性囊腺癌是主要的恶性肿瘤（11.3%）。发现转移性肿瘤双侧卵巢受累的比例为72%，而恶性浆液性肿瘤双侧受累的比例为49.5%。交界性浆液性肿瘤比交界性黏液性肿瘤更常出现双侧受累（27.4%对15.7%）。大多数恶性肿瘤表现为Ⅲ期（60%）或Ⅱ期（20%）疾病。Ⅰ期肿瘤的总生存率为85%，Ⅱ期为65%，Ⅲ期为30%，Ⅳ期肿瘤为15.5%。
我们注意到恶性肿瘤的就诊年龄较早。成熟畸胎瘤是第二常见的良性肿瘤（仅次于浆液性囊腺瘤）。我们还注意到子宫内膜样肿瘤的比例较低。Ⅳ期肿瘤数量较少，大量恶性卵巢肿瘤在较早年龄出现。
