Kaur Ishwarpreet, Singh Amarjeet, Suri Vanita, Kishore Kamal, Rana Satya Vati, Sahni Nancy, Bhattacharya Sudip
Department of Community Medicine and School of Public Health, Postgraduate Institute of Medical Education and Research (PGIMER), Chandigarh, India.
Department of Obstetrics and Gynecology, Postgraduate Institute of Medical Education and Research (PGIMER), Chandigarh, India.
J Educ Health Promot. 2023 Jun 30;12:190. doi: 10.4103/jehp.jehp_21_23. eCollection 2023.
Polycystic ovarian syndrome (PCOS) is a complex and heterogeneous disorder affecting various body organs. Menstrual irregularity, anovulation, and many cosmetic issues faced by PCOS patients endanger the essence of being a woman and may have a deleterious impact on their health-related quality of life (HRQOL). This study aimed to assess HRQOL in patients with PCOS and to identify the clinical and socio-demographic factors that might predict poor HRQOL.
This cross-sectional study was carried out in the tertiary care hospital in India. A total of 275 women visiting the same setting and diagnosed with PCOS were included. The participants' quality of life was studied using a disease-specific HRQOL questionnaire. Information regarding clinical and socio-demographics was collected using the interviewer schedule. For evaluating the predictors of HRQOL in PCOS subjects, analysis of variance and independent -test was applied. For subgroup analysis, the post hoc (Gabriel) test was applied.
The average total score of HRQOL of the study participants was 125.41 ± 29.1. The lowest weighted mean score was for menstrual problems. Among the socio-demographic variables, age and educational level influenced the HRQOL scores. Highly educated women reported the poorest HRQOL. The analysis of variance also indicated a significant variation in HRQOL scores among body mass index categories [F (4,270) = 5.09, = <.001] and hirsutism status [F (2,272) = 14.222, =<.001].
Menstrual irregularity, hirsutism, increased body mass index, educational status, and age are critical in altering HRQOL in PCOS cases. Clinicians should inquire about the HRQOL of patients with severe clinical manifestations and appropriate support must be provided during patient care.
多囊卵巢综合征（PCOS）是一种影响身体多个器官的复杂异质性疾病。月经不规律、无排卵以及PCOS患者面临的许多美容问题危及女性的本质，可能对其健康相关生活质量（HRQOL）产生有害影响。本研究旨在评估PCOS患者的HRQOL，并确定可能预测HRQOL较差的临床和社会人口学因素。
本横断面研究在印度的一家三级护理医院进行。共纳入275名前来该机构就诊并被诊断为PCOS的女性。使用特定疾病的HRQOL问卷研究参与者的生活质量。通过访谈时间表收集有关临床和社会人口学的信息。为了评估PCOS受试者HRQOL的预测因素，应用方差分析和独立检验。对于亚组分析，应用事后（Gabriel）检验。
研究参与者HRQOL的平均总分是125.41±29.1。加权平均分最低的是月经问题。在社会人口学变量中，年龄和教育水平影响HRQOL分数。受教育程度高的女性报告的HRQOL最差。方差分析还表明，体重指数类别[F（4,270）=5.09，P<0.001]和多毛症状态[F（2,272）=14.222，P<0.001]之间的HRQOL分数存在显著差异。
月经不规律、多毛症、体重指数增加、教育状况和年龄对改变PCOS患者的HRQOL至关重要。临床医生应询问有严重临床表现患者的HRQOL，并且在患者护理期间必须提供适当的支持。
