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多脾综合征婴儿坏疽性肺炎球菌感染的成功管理

The Successful Management of Gangrenous Pneumococcal Infection in an Infant With Polysplenia Syndrome.

作者信息

Garout Wallaa

机构信息

Department of Pediatrics, King Abdulaziz University Hospital, Jeddah, SAU.

出版信息

Cureus. 2023 Jul 5;15(7):e41390. doi: 10.7759/cureus.41390. eCollection 2023 Jul.

DOI:10.7759/cureus.41390
PMID:37546058
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10401484/
Abstract

This study describes the successful management of gangrenous pneumococcal infection in an infant with polysplenia, a rare congenital malformation characterized by multiple aberrant nodules of splenic tissue. The patient, a three-month-old girl with congenital heart defects and incomplete vaccination, presented with fever, irritability, and oxygen desaturation, followed by erythematous skin changes. The diagnosis revealed sepsis caused by , accompanied by extensive gangrenous skin lesions and signs of disseminated intravascular coagulation. Polysplenia was incidentally discovered during radiological investigation. Aggressive resuscitation measures and prolonged antibiotic administration led to significant improvement, including regression of skin lesions. This case emphasizes the importance of timely immunization and parental awareness for infants with spleen-related congenital malformations. Screening for undiagnosed malformative defects in congenital heart disease patients can aid in early detection and prevention of life-threatening complications. The successful management demonstrates the critical role of pediatric intensive care units in treating severe systemic infections.

摘要

本研究描述了对一名患有多脾症的婴儿坏疽性肺炎球菌感染的成功治疗,多脾症是一种罕见的先天性畸形,其特征是存在多个异常的脾组织结节。该患者为一名三个月大的女孩,患有先天性心脏缺陷且疫苗接种不完全,出现发热、易激惹和氧饱和度下降,随后出现皮肤红斑变化。诊断显示为由……引起的败血症,伴有广泛的坏疽性皮肤病变和弥散性血管内凝血迹象。多脾症是在放射学检查中偶然发现的。积极的复苏措施和长期使用抗生素导致病情显著改善,包括皮肤病变消退。该病例强调了及时免疫接种以及家长对患有与脾脏相关先天性畸形婴儿的认知的重要性。对先天性心脏病患者未诊断出的畸形缺陷进行筛查有助于早期发现并预防危及生命的并发症。成功的治疗证明了儿科重症监护病房在治疗严重全身感染中的关键作用。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4cd9/10401484/e4129614b565/cureus-0015-00000041390-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4cd9/10401484/c16ea437bcbe/cureus-0015-00000041390-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4cd9/10401484/e4129614b565/cureus-0015-00000041390-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4cd9/10401484/c16ea437bcbe/cureus-0015-00000041390-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4cd9/10401484/e4129614b565/cureus-0015-00000041390-i02.jpg

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BMJ Case Rep. 2022 May 19;15(5):e249514. doi: 10.1136/bcr-2022-249514.
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