Li Pi-I, Guo How-Ran
Department of Family Medicine, Chi Mei Medical Center, Tainan 710, Taiwan.
Department of Pharmacy, Chia Nan University of Pharmacy and Science, Tainan 717, Taiwan.
World J Diabetes. 2023 Jul 15;14(7):1091-1102. doi: 10.4239/wjd.v14.i7.1091.
Cardiovascular disease (CVD) is the leading cause of death globally, and diabetes mellitus (DM) is a well-established risk factor. Among the risk factors for CVD, DM is a major modifiable factor. In the fatal CVD outcomes, acute myocardial infarction (AMI) is the most common cause of death.
To develop a long-term quality-of-care score for predicting the occurrence of AMI among patients with type 2 DM on the basis of the hypothesis that good quality of care can reduce the risk of AMI in patients with DM.
Using Taiwan's Longitudinal Cohort of Diabetes Patient Database and the medical charts of a medical center, we identified incident patients diagnosed with type 2 DM from 1999 to 2003 and followed them until 2011. We constructed a summary quality-of-care score (with values ranging from 0 to 8) with process indicators (frequencies of HbA and lipid profile testing and urine, foot and retinal examinations), intermediate outcome indicators (low-density lipoprotein, blood pressure and HbA), and co-morbidity of hypertension. The associations between the score and the incidence of AMI were evaluated using Cox regression models.
A total of 7351 patients who had sufficient information to calculate the score were enrolled. In comparison with participants who had scores ≤ 1, those with scores between 2 and 4 had a lower risk of developing AMI [adjusted hazard ratio (AHR) = 0.71; 95% confidence interval (95%CI): 0.55-0.90], and those with scores ≥ 5 had an even lower risk (AHR = 0.37; 95%CI: 0.21-0.66).
Good quality of care can reduce the risk of AMI in patients with type 2 DM. The quality-of-care score developed in this study had a significant association with the risk of AMI and thus can be applied to guiding the care for these patients.
心血管疾病(CVD)是全球主要的死亡原因,而糖尿病(DM)是公认的风险因素。在心血管疾病的风险因素中,糖尿病是一个主要的可改变因素。在致命的心血管疾病结局中,急性心肌梗死(AMI)是最常见的死亡原因。
基于优质护理可降低糖尿病患者发生急性心肌梗死风险的假设,制定一个长期护理质量评分,以预测2型糖尿病患者急性心肌梗死的发生。
利用台湾糖尿病患者纵向队列数据库和某医疗中心的病历,我们确定了1999年至2003年被诊断为2型糖尿病的新发患者,并对他们进行随访至2011年。我们构建了一个护理质量综合评分(取值范围为0至8),该评分包括过程指标(糖化血红蛋白和血脂谱检测以及尿液、足部和视网膜检查的频率)、中间结局指标(低密度脂蛋白、血压和糖化血红蛋白)以及高血压合并症。使用Cox回归模型评估该评分与急性心肌梗死发病率之间的关联。
共有7351名有足够信息计算评分的患者入组。与评分≤1的参与者相比,评分在2至4之间的参与者发生急性心肌梗死的风险较低[调整后危险比(AHR)=0.71;95%置信区间(95%CI):0.55 - 0.90],评分≥5的参与者风险更低(AHR = 0.37;95%CI:0.21 - 0.66)。
优质护理可降低2型糖尿病患者发生急性心肌梗死的风险。本研究制定的护理质量评分与急性心肌梗死风险显著相关,因此可用于指导这些患者的护理。