Geng Zhiyu, Li Chunqing, Kong Hao, Song Linlin
Department of Anesthesiology, Peking University First Hospital, Beijing, China.
Front Med (Lausanne). 2023 Jul 20;10:1181503. doi: 10.3389/fmed.2023.1181503. eCollection 2023.
Previous research showed the use of supraglottic airways in obstetric anesthesia. The relevant evidence of laryngeal mask airway (LMA) on maternal and neonatal outcomes is still limited. We aimed to assess the maternal and neonatal outcomes when the LMA Supreme was used for cesarean section under general anesthesia.
We included all patients who underwent general anesthesia for cesarean section between January 2010 and December 2019. Propensity score matching was used to reduce potential bias from non-random selection of airway intervention. The primary outcome was adverse maternal and neonatal outcomes defined as maternal regurgitation, aspiration, hypoxemia, and low neonatal Apgar scores. Secondary outcomes included patient admission to the intensive care unit, neonate required tracheal intubation, external cardiac massage, and admission to the neonatal intensive care unit.
A total of 723 patients were included in the analysis; of whom, 221 received Supreme laryngeal mask airway (LMA group) and 502 were intubated with an endotracheal tube (ETT group). After propensity score matching, 189 patients remained in each group. No episode of regurgitation and aspiration occurred in both groups. There was no difference in the rates of Apgar score below 7 at 1 min (14.3% LMA group vs. 15.3% ETT group, OR 0.931, 95% CI 0.574 to 1.510, = 0.772) and 5 min (3.7% vs. 4.2%, OR 0.875, 95% CI 0.324 to 2.365, = 0.792). No difference was observed in the secondary outcomes between the two groups.
The LMA Supreme was not associated with higher adverse maternal and neonatal outcomes when compared to an endotracheal tube for cesarean section under general anesthesia. It might be considered an alternative to tracheal intubation in obstetric practice.
既往研究显示了声门上气道在产科麻醉中的应用。喉罩气道(LMA)对母婴结局的相关证据仍然有限。我们旨在评估在全身麻醉下行剖宫产术时使用 Supreme 喉罩的母婴结局。
我们纳入了 2010 年 1 月至 2019 年 12 月期间所有接受全身麻醉剖宫产术的患者。采用倾向评分匹配法以减少气道干预非随机选择带来的潜在偏倚。主要结局是不良母婴结局,定义为产妇反流、误吸、低氧血症和新生儿低 Apgar 评分。次要结局包括患者入住重症监护病房、新生儿需要气管插管、体外心脏按压以及入住新生儿重症监护病房。
共有 723 例患者纳入分析;其中,221 例接受 Supreme 喉罩气道(LMA 组),502 例接受气管内插管(ETT 组)。经过倾向评分匹配后,每组各有 189 例患者。两组均未发生反流和误吸事件。两组在 1 分钟时 Apgar 评分低于 7 分的发生率(LMA 组为 14.3%,ETT 组为 15.3%,OR 0.931,95%CI 0.574 至 1.510,P = 0.772)以及 5 分钟时(3.7%对 4.2%,OR 0.875,95%CI 0.324 至 2.365,P = 0.792)均无差异。两组次要结局未见差异。
与全身麻醉下行剖宫产术时使用气管内插管相比,Supreme 喉罩与更高的不良母婴结局无关。在产科实践中它可被视为气管插管的一种替代方法。