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胃癌脉络膜转移:一例病例报告并文献复习。

Choroidal metastasis from gastric cancer: A case report and review of the literature.

机构信息

Department of Pathology, Hangzhou Red Cross Hospital, Zhejiang, China, 310003.

Department of Clinical Laboratory, Hangzhou Red Cross Hospital, Zhejiang, China, 310003.

出版信息

J Int Med Res. 2023 Aug;51(8):3000605231187943. doi: 10.1177/03000605231187943.

DOI:10.1177/03000605231187943
PMID:37548314
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10408333/
Abstract

Choroidal metastatic tumours from gastric cancer (GC) are rare compared with breast and lung cancer. Here, we report a patient with GC who presented to our ophthalmology clinic with a one-week history of left eye visual disorder and pain. Fundoscopic and B-scan examinations suggested a choroidal metastatic tumour. Computed tomography (CT) and magnetic resonance imaging (MRI) scans confirmed our initial diagnosis. Histopathology and immunohistochemical findings showed the tumour most likely originated from the gastrointestinal tract. Although the patient was well after eye removal, he died two months after surgery. Metastasis of GC should be a consideration when a patient with a history of GC presents with eye pain, decreased vision, and/or high intraocular pressure.

摘要

与乳腺癌和肺癌相比,源于胃癌的脉络膜转移瘤较为少见。在此,我们报告一例胃癌患者,因左眼视力障碍和疼痛一周就诊于我院眼科。眼底和 B 型超声检查提示脉络膜转移瘤。计算机断层扫描(CT)和磁共振成像(MRI)扫描证实了我们的初步诊断。组织病理学和免疫组织化学检查结果显示,该肿瘤最有可能来源于胃肠道。尽管患者在眼球摘除后情况良好,但在手术后两个月死亡。对于有胃癌病史的患者,当出现眼痛、视力下降和/或高眼压时,应考虑胃癌转移的可能。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/221d/10408333/cba6d2402304/10.1177_03000605231187943-fig3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/221d/10408333/8d1ed4def1bb/10.1177_03000605231187943-fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/221d/10408333/05c8c21bfd30/10.1177_03000605231187943-fig2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/221d/10408333/cba6d2402304/10.1177_03000605231187943-fig3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/221d/10408333/8d1ed4def1bb/10.1177_03000605231187943-fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/221d/10408333/05c8c21bfd30/10.1177_03000605231187943-fig2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/221d/10408333/cba6d2402304/10.1177_03000605231187943-fig3.jpg

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本文引用的文献

1
Spontaneous rupture of the eyeball due to choroidal metastasis of gastric carcinoma: A case report.胃癌脉络膜转移致眼球自发性破裂:一例报告
Medicine (Baltimore). 2019 Oct;98(40):e17441. doi: 10.1097/MD.0000000000017441.
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Choroidal metastasis from gastric adenocarcinoma: A rare case.胃腺癌脉络膜转移:1例罕见病例。
Dig Liver Dis. 2019 May;51(5):746. doi: 10.1016/j.dld.2019.01.019. Epub 2019 Feb 5.
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New concepts in the diagnosis and management of choroidal metastases.脉络膜转移瘤的诊断和治疗新概念。
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Clin Ophthalmol. 2018 Aug 17;12:1459-1463. doi: 10.2147/OPTH.S172464. eCollection 2018.
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Gastric Adenocarcinoma with Systemic Metastasis Involving the Intraocular Choroid and Duodenum.伴有全身转移累及眼内脉络膜和十二指肠的胃腺癌
Clin Endosc. 2018 Jan;51(1):95-98. doi: 10.5946/ce.2017.049. Epub 2017 May 22.
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Ophthalmology. 2014 Jan;121(1):352-357. doi: 10.1016/j.ophtha.2013.07.014. Epub 2013 Aug 26.
10
Choroidal and cutaneous metastasis from gastric adenocarcinoma.胃腺癌的脉络膜和皮肤转移。
World J Gastroenterol. 2013 Mar 7;19(9):1485-8. doi: 10.3748/wjg.v19.i9.1485.