School of Medicine, College of Health Sciences, Makerere University, Kampala, Uganda.
Faculty of Medicine, Gulu University, Gulu, Uganda.
PLoS One. 2023 Aug 7;18(8):e0289546. doi: 10.1371/journal.pone.0289546. eCollection 2023.
Rheumatic and musculoskeletal disorders (RMDs) are associated with cardiovascular diseases (CVDs), with hypertension being the most common. We aimed to determine the prevalence of high blood pressure (HBP), awareness, treatment, and blood pressure control among patients with RMDs seen in a Rheumatology clinic in Uganda.
We conducted a cross-sectional study at the Rheumatology Clinic of Mulago National Referral Hospital (MNRH), Kampala, Uganda. Socio-demographic, clinical characteristics and anthropometric data were collected. Multivariable logistic regression was performed using STATA 16 to determine factors associated with HBP in patients with RMDs.
A total of 100 participants were enrolled. Of these, majority were female (84%, n = 84) with mean age of 52.1 (standard deviation: 13.8) years and median body mass index of 28 kg/m2 (interquartile range (IQR): 24.8 kg/m2-32.9 kg/m2). The prevalence of HBP was 61% (n = 61, 95% CI: 51.5-70.5), with the majority (77%, n = 47, 95% CI: 66.5-87.6) being aware they had HTN. The prevalence of HTN was 47% (n = 47, 37.2-56.8), and none had it under control. Factors independently associated with HBP were age 46-55years (adjusted prevalence ratio (aPR): 2.5, 95% confidence interval (CI): 1.06-5.95), 56-65 years (aPR: 2.6, 95% CI: 1.09-6.15), >65 years (aPR: 2.5, 95% CI: 1.02-6.00), obesity (aPR: 3.7, 95% CI: 1.79-7.52), overweight (aPR: 2.7, 95% CI: 1.29-5.77).
There was a high burden of HBP among people with RMDs in Uganda with poor blood pressure control, associated with high BMI and increasing age. There is a need for further assessment of the RMD specific drivers of HBP and meticulous follow up of patients with RMDs.
风湿和肌肉骨骼疾病（RMDs）与心血管疾病（CVDs）相关，其中高血压最为常见。我们旨在确定在乌干达一家风湿病诊所就诊的 RMD 患者中高血压（HBP）的患病率、知晓率、治疗率和血压控制率。
我们在乌干达坎帕拉的穆拉戈国家转诊医院（MNRH）风湿病科进行了一项横断面研究。收集了社会人口统计学、临床特征和人体测量学数据。使用 STATA 16 进行多变量逻辑回归，以确定 RMD 患者中与 HBP 相关的因素。
共纳入 100 名参与者。其中，大多数为女性（84%，n=84），平均年龄为 52.1（标准差：13.8）岁，平均体重指数为 28kg/m2（四分位间距（IQR）：24.8kg/m2-32.9kg/m2）。高血压的患病率为 61%（n=61，95%CI：51.5-70.5%），其中大多数（77%，n=47，95%CI：66.5-87.6%）知晓自己患有高血压。高血压的患病率为 47%（n=47，37.2-56.8%），且无人血压得到控制。与 HBP 独立相关的因素是 46-55 岁（调整后的患病率比（aPR）：2.5，95%置信区间（CI）：1.06-5.95）、56-65 岁（aPR：2.6，95%CI：1.09-6.15）、>65 岁（aPR：2.5，95%CI：1.02-6.00）、肥胖（aPR：3.7，95%CI：1.79-7.52）、超重（aPR：2.7，95%CI：1.29-5.77）。
乌干达 RMD 患者的 HBP 负担沉重，血压控制不佳，与较高的 BMI 和年龄增长有关。需要进一步评估 RMD 特有的 HBP 驱动因素，并对 RMD 患者进行精心随访。
