Venom and Biotherapeutics Molecules Laboratory, Department of Biotechnology, Biotechnology Research Center, Pasteur Institute of Iran, Tehran, Iran.
Department of Biology, Shahed University, Tehran, Iran.
Curr Pharm Biotechnol. 2024;25(6):676-693. doi: 10.2174/1389201024666230807161200.
Drug delivery is an important topic that has attracted the attention of researchers in recent years. Albumin nanoparticles play a significant role in drug delivery as a carrier due to their unique characteristics. Albumin is non-toxic, biocompatible, and biodegradable. Its structure is such that it can interact with different drugs, which makes the treatment of the disease faster and also reduces the side effects of the drug. Albumin nanoparticles can be used in the diagnosis and treatment of many diseases, including cancer, diabetes, Alzheimer's, etc. These nanoparticles can connect to some compounds, such as metal nanoparticles, antibodies, folate, etc. and create a powerful nanostructure for drug delivery. In this paper, we aim to investigate albumin nanoparticles in carrier format for drug delivery application. In the beginning, different types of albumin and their preparation methods were discussed, and then albumin nanoparticles were discussed in detail in diagnosing and treating various diseases.
药物递送是近年来引起研究人员关注的一个重要课题。白蛋白纳米粒作为载体在药物递送上发挥着重要作用，因为其具有独特的特性。白蛋白无毒、生物相容且可生物降解。其结构可以与不同的药物相互作用，这使得疾病的治疗更快，同时也减少了药物的副作用。白蛋白纳米粒可用于多种疾病的诊断和治疗，包括癌症、糖尿病、阿尔茨海默病等。这些纳米粒可以与一些化合物（如金属纳米粒、抗体、叶酸等）结合，形成用于药物递送的强大纳米结构。本文旨在研究作为药物递送载体的白蛋白纳米粒。首先讨论了不同类型的白蛋白及其制备方法，然后详细讨论了白蛋白纳米粒在诊断和治疗各种疾病中的应用。
