Qiu Shuyao, Yang Liqiang, Zhong Jianwen, Luo Xiangqian, Liu Dabo
Pediatric Otolaryngology Department of Shenzhen Hospital，Southern Medical University，Shenzhen，518000，China.
Lin Chuang Er Bi Yan Hou Tou Jing Wai Ke Za Zhi. 2023 Aug;37(8):656-657;666. doi: 10.13201/j.issn.2096-7993.2023.08.011.
Two children with late-onset congenital central hypoventilation syndrome were reported, one of whom was male and had no abnormal manifestations after birth, respiratory failure occurs at the age of 1 year and 6 months. After being hospitalized, he was treated with oxygen inhalation and non-invasive ventilation, but carbon dioxide retention could not be corrected. After one month of tracheal intubation, he was failure to wean from ventilator, so tracheostomy was performed. He needs a ventilator to help breath while sleeping, and can breath autonomously during the day without ventilator. The other case was a female, with no abnormalities after birth. At the age of 11 months, she developed respiratory failure. During sleep, the child needs non-invasive assisted ventilation through a nasal mask, and during the day, she breathed autonomously.Two patients were followed up forever 2 years and their growth and development were normal.
报道了两名迟发性先天性中枢性低通气综合征患儿，其中一名为男性，出生后无异常表现，1岁6个月时发生呼吸衰竭。住院后，给予吸氧及无创通气治疗，但二氧化碳潴留无法纠正。气管插管1个月后，脱机失败，遂行气管切开术。他睡觉时需要呼吸机辅助呼吸，白天可自主呼吸。另一例为女性，出生后无异常。11个月时出现呼吸衰竭。睡眠期间，患儿需要通过鼻面罩进行无创辅助通气，白天可自主呼吸。两名患者随访2年，生长发育正常。
