Int J Periodontics Restorative Dent. 2023 Oct 24(7):s118-s128. doi: 10.11607/prd.6395.
This retrospective clinical study compared two different professional maintenance therapy (MT) approaches (with and without periodic removal and decontamination of prosthetic components) on peri-implant inflammatory clinical and biochemical parameters after 5 years of implant function. A retrospective analysis based on patient records was used to assess inflammatory clinical and biochemical parameters around dental implants placed by the same clinician in a private practice. The Plaque Index (PI), peri-implant probing depth (PPD), mucosal recession (REC), bleeding on probing (BOP), and radiographic marginal bone level were determined at baseline and at each follow-up year. Moreover, at the last follow-up visit, the peri-implant intrasulcular levels of active metalloproteinasis 8 (aMMP-8) were also assessed. All participants were under MT with a 6-month recall interval. A total of 92 patients with 132 implants were selected. At the end of the study period, 12 patients with 12 implants were classified as dropouts. The remaining 80 patients and 120 implants were classified into two groups: Group 1 (42 patients, 62 implants) received MT with periodic removal and decontamination of prosthetic components; Group 2 (38 patients, 58 implants) received MT without periodic removal and decontamination of prosthetic components. No statistical differences were found between the groups regarding PI, PPD, and REC. Group 1 presented a statistically significant higher number of sites with BOP (12.4% vs 6.2%). Marginal bone loss was statistically higher in Group 2 than in Group 1 (0.23 ± 0.6 mm vs 0.78 ± 0.3 mm). Intrasulcular levels of aMMP-8 were statistically higher in Group 1 than in Group 2. The supplemental application of periodic removal and decontamination of prosthetic components during MT had a significantly positive effect on the inflammatory status of peri-implant tissues.
这项回顾性临床研究比较了两种不同的专业维护治疗（MT）方法（有和没有定期去除和消毒修复体部件）在植入后 5 年内对种植体周围炎症临床和生化参数的影响。基于患者记录的回顾性分析用于评估由同一位临床医生在私人诊所中放置的牙科植入物周围的炎症临床和生化参数。在基线和每个随访年确定菌斑指数（PI）、种植体探诊深度（PPD）、黏膜退缩（REC）、探诊出血（BOP）和放射状边缘骨水平。此外，在最后一次随访时，还评估了种植体周沟内活性金属蛋白酶 8（aMMP-8）的水平。所有参与者均接受每 6 个月一次的 MT 治疗。共选择了 92 名患者的 132 个种植体。在研究结束时，12 名患者的 12 个种植体被归类为脱落者。其余 80 名患者和 120 个种植体被分为两组：组 1（42 名患者，62 个种植体）接受定期去除和消毒修复体部件的 MT；组 2（38 名患者，58 个种植体）接受不进行定期去除和消毒修复体部件的 MT。两组间 PI、PPD 和 REC 无统计学差异。组 1 探诊出血的位点比例显著较高（12.4% vs 6.2%）。组 2 的边缘骨丧失明显高于组 1（0.23 ± 0.6 mm vs 0.78 ± 0.3 mm）。组 1 的种植体周沟内 aMMP-8 水平显著高于组 2。MT 期间定期去除和消毒修复体部件的补充应用对种植体周围组织的炎症状态有显著的积极影响。
