Delisle M J, Hannequin P, Liehn J C, Gibold C, Maes B, Vaudrey C, Pochart J M, Morel M
Bull Cancer. 1986;73(2):165-70.
Between 1967 and 1984, 600 cases of clinically diagnosed thyroid carcinoma were collected in an area (Champagne-Ardenne) of about 1,500,000 inhabitants. During this period, the complete collection of the cases was progressively ensured by involving all the general practitioners and by creating a cooperative multidisciplinary group. The collected data were sex, age at diagnosis, histological classification and clinical extension in TNM system. We found 19 patients with previous neck irradiation. Thyroid cancer was diagnosed in association with thyrotoxicosis in 36 patients: 13 Graves disease and 23 nodular hyperthyroidism. Incidence rates were estimated on a well defined population of two districts (850,000 inhabitants) and limited to the last four years. The following results were obtained: incidence 4.3/100,000/year, age-specific incidence progressively increasing up to a value of 10/000,000/year in the course of the fifth decade. Sex-ratio was 0.26.
1967年至1984年间，在一个约有150万居民的地区（香槟-阿登大区）收集了600例临床诊断为甲状腺癌的病例。在此期间，通过动员所有全科医生并组建一个多学科合作小组，逐步实现了病例的完整收集。收集的数据包括性别、诊断时的年龄、组织学分类以及TNM系统中的临床分期。我们发现有19例患者曾接受过颈部放疗。36例患者的甲状腺癌与甲状腺毒症相关：13例为格雷夫斯病，23例为结节性甲状腺功能亢进。发病率是根据两个区（85万居民）的明确人群估算得出的，且仅限于最近四年。得出以下结果：发病率为每年4.3/10万，年龄别发病率在第五个十年中逐渐上升，最高达到每年10/10万。性别比为0.26。
