Laws David, Poff Christopher D, Heyboer Ethan M, Blakey Simon B
Department of Chemistry, Emory University, Atlanta, Georgia 30322, USA.
Chem Soc Rev. 2023 Aug 29;52(17):6003-6030. doi: 10.1039/d3cs00325f.
Planar chirality is an important form of molecular chirality that can be utilized to induce enantioselectivity when incorporated into transition metal catalysts. However, due to synthetic constraints, the use of late transition metal planar chiral complexes to conduct enantioselective transformations has been limited. Additionally, the published methods surrounding the stereochemical assignment of planar chiral compounds are sometimes conflicting, making proper assignment difficult. This review aims to provide clarity on the methods available to assign planar chirality and provide an overview on the synthesis and use of late transition metal planar chiral complexes as enantioselective catalysts.
平面手性是分子手性的一种重要形式，当它被引入过渡金属催化剂中时可用于诱导对映选择性。然而，由于合成上的限制，使用后过渡金属平面手性配合物进行对映选择性转化一直受到限制。此外，围绕平面手性化合物立体化学归属的已发表方法有时相互矛盾，使得正确归属变得困难。本综述旨在阐明用于确定平面手性的可用方法，并概述后过渡金属平面手性配合物作为对映选择性催化剂的合成与应用。
